摘要
目的:比较ⅢB期非小细胞肺癌微创手术与开放手术的临床效果。方法:研究对象为80例ⅢB期非小细胞肺癌患者,按照入院先后顺序分为两组,每组40例。对照组采用开放手术治疗,观察组实施微创手术治疗,比较不同手术方法应用效果。结果:观察组手术术中出血量、术后引流量、置管时间以及住院时间、并发症发生率少于对照组(P<0.05),术后的CD_(3)^(+)、CD_(4)^(+)、CD_(8)^(+)细胞分数高于对照组(P<0.05),淋巴结清除率观察组与对照组未见明显差异。结论:ⅢB期非小细胞肺癌采用微创手术治疗,能够保证淋巴结清除率、且造成的创伤小、住院时间短、并发症发生率少,对机体免疫功能造成的影响小。
Objective:To compare the clinical outcomes of VATS surgery and open surgery for stage Ⅲ B non-small cell lung cancer.Methods:80 patients with stage ⅢB non-small cell lung cancer were divided into observation group(n=40)and reference group(n=40),the reference group was treated with open surgery,and the observation group was treated with VATS surgery,to compare the effects of different surgical methods.Results:There was significant difference between the observation group and the reference group in the intraoperative blood loss,postoperative drainage,the drainage tube indwelling time,hospital stay,complication rate and postoperative CD_(3)^(+)、CD_(4)^(+)、CD_(8)^(+)cell scores(P<0.05).There was no significant difference between the lymph node clearance rate observation group and the control group.Conclusion:The VATS surgery for stage ⅢB non-small cell lung cancer can ensure the clearance rate of lymph nodes,and less trauma,shorter hospital stay,less complication rate,and less impact on immune function.
作者
安小康
丁钎州
刘亚龙
陈涛
郭明杰
周冉
黄智超
马雪瑶
张国瑜
董彦军
杨忠信
郑先杰
张双林
AN Xiaokang;DING Qianzhou;LIU Yalong;CHEN Tao;GUO Mingjie;ZHOU Ran;HUANG Zhichao;MA Xueyao;ZHANG Guoyu;DONG yanjun;YANG Zhongxin;ZHENG Xianjie;ZHANG Shuanglin(Department of Thoracic Srugery The First Affiliated Hospital of Henan University,Kaifeng 475000,CHN)
出处
《河南大学学报（医学版）》
CAS
2022年第2期123-126,共4页
Journal of Henan University:Medical Science
基金
河南省科技攻关计划(GG2019033)
河南省医学科技攻关计划(2018020310)
新乡市科技攻关计划(212102310700)。
关键词
非小细胞肺癌
微创手术
开放手术
免疫功能
non-small cell lung cancer
VATS surgery
open surgery
immune function
