摘要
纳米硒因其独特的理化性质和生物活性受到广泛关注,在食品、医药、农业等领域具有潜在的应用价值。多糖作为软模板能很好地修饰纳米硒,形成一种稳定、低毒、高生物活性的多糖纳米硒。因此,寻找高效的多糖纳米硒的制备方法以及研究其结构与生物活性的关系已经成为近几年的热点。文章重点总结了以多糖为模板,抗坏血酸为还原剂,无机硒为硒供体,利用化学还原合成多糖纳米硒的方法,并概述了目前用于表征多糖纳米硒的技术,同时对多糖纳米硒的抗肿瘤和抗氧化活性进行了综述,旨在为多糖纳米硒的制备与开发提供理论基础和研究思路。
Selenium nanoparticles has attracted extensive attention because of its unique physical and chemical properties and biological activity,and has potential application value in food,medicine,agriculture and other fields.Polysaccharide as a soft template can modify selenium nanoparticles well and form a stable,low toxicity and high bioactivity selenium nanoparticles polysaccharides.Therefore,it has become a hot topic in recent years to find efficient preparation methods of selenium nanoparticles polysaccharides and to study the relationship between its structure and biological activity.This paper mainly summarizes the synthesis methods of selenium nanoparticles polysaccharides by chemical reduction with the polysaccharide as the template,ascorbic acid as reducing agent,inorganic selenium as selenium donor,and summarizes the current technology used for characterization of selenium nanoparticles polysaccharides,at the same time antitumor and antioxidant activity of selenium nanoparticles polysaccharides were reviewed,aimed to provide theoretical basis and research train of thought at the preparation and development of selenium nanoparticles polysaccharides.
作者
史梦华
任瑞芳
郑涵予
邓婕
程水源
马晓龙
张绍鹏
SHI Menghua;REN Ruifang;ZHENG Hanyu;DENG Jie;CHENG Shuiyuan;MA Xiaolong;ZHANG Shaopeng(National R&D Center for Se-Rich Agricultural Products Processing,Hubei Engineering Research Center for Deep Processing of Green Se-Rich Agricultural Products,Wuhan Polytechnic University,Wuhan 430023,China;College of Life Science and Technology,Wuhan Polytechnic University,Wuhan 430023,China;School of Modern Industry for Selenium Science and Engineering,Wuhan Polytechnic University,Wuhan 430040,China;Vegetable Research Institute of Wuhan Academy of Agricultural Sciences,Wuhan 430345,China)
出处
《食品科技》
CAS
北大核心
2022年第3期8-14,共7页
Food Science and Technology
基金
2020年武汉市应用基础前沿专项(2020020601012297)。
关键词
多糖纳米硒
表征
生物活性
selenium nanoparticles polysaccharides
characterization
biological activity
