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维持性血液透析对老年慢性肾衰竭合并心力衰竭患者心脏功能及血浆NT-proBNP的影响 被引量:4

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摘要 目的:探讨老年慢性肾衰竭(CRF)合并心力衰竭患者通过采取维持性血液透析(MHD)的治疗方式,对患者心脏功能、血浆N末端B型利钠肽前体(NT-proBNP)的影响。方法:选取90例老年CRF患者,按是否合并心力衰竭分成合并心衰组50例与未合并心衰组40例,且选取同期健康体检的50例志愿者为对照组,老年CRF均采取MHD治疗3个月,比较治疗前后的心脏功能与血浆NT-proBNP水平变化。结果:合并心衰组经MHD治疗3个月后,在左心室内径缩短率(FS)、室间隔厚度(IVST)、左心室质量指数(LVMI)水平上均较治疗前降低,左心室射血分数(LVEF)较治疗前提高(P<0.05);在治疗前,合并心衰组与未合并心衰组的血浆NT-proBNP水平均高于对照组,合并心衰组随着心功能损害程度的加重血浆NT-proBNP水平也不断升高;治疗3个月后合并心衰组与未合并心衰组在NT-proBNP水平上均较治疗前降低(P<0.05);Spearman线性相关性检验分析,血浆NT-proBNP同IVST、LVMI呈正相关,与FS、LVEF呈负相关。结论:针对老年CRF合并心力衰竭,实施规范化的MHD治疗可以改善心脏功能,降低血浆NT-proBNP水平。
作者 李绪泽
出处 《医学食疗与健康》 2022年第5期45-48,共4页 Medical Diet and Health
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