摘要
可降解鼻窦药物支架(BCES)是近年来应用于临床的一类植入在功能性鼻内镜鼻窦手术(FESS)患者术腔中,预防术后粘连、减少炎症的可降解药物支架类产品。该产品利用其支撑作用保持术后中鼻道开放,避免中鼻甲与鼻腔外侧壁粘连,利于窦口开放;其携带的药物在病变部位定量释放,抑制炎性反应及鼻息肉增生,解决鼻用激素不易到达中鼻道深部的问题,为慢性鼻窦炎患者的术后继续治疗提供了一种新的方式。目前,国内外多家医疗机构已将其用于临床及实验研究,现将其发展历史、作用和种类、安全性及有效性等进行综述。
Bioabsorbable corticosteroid-eluting sinus stents(BCES)is a kind of biodegradable medical stent that has been implanted in the operative cavity of patients undergoing functional endoscopic sinus surgery(FESS)in recent years to prevent postoperative adhesion and reduce inflammation.The product is used by its supporting effect to keep the nasal passages open after surgery,avoiding the adhesion between the middle turbinate and the lateral wall.The drugs carried by it are released quantitatively at the lesion site,which can inhibit inflammatory reaction and nasal polyp hyperplasia,solve the problem that nasal spray hormone is not easy to reach the deep of nasal passages,and provide a new way for patients with chronic sinusitis to continue treatment after surgery.At present,it has been used in clinical and experimental studies by many medical institutions at home and abroad.This paper reviews its development history,role and type,safety and efficacy.
作者
张军军
丁雪瑞
ZHANG Junjun;DING Xuerui(Department of Otolaryngology Head and Neck Surgery,Tangdu Hospital,Air Force Medical University,Xi’an 710038,China)
出处
《陕西医学杂志》
CAS
2022年第5期638-640,F0003,共4页
Shaanxi Medical Journal
关键词
可降解鼻窦药物支架
慢性鼻窦炎
鼻息肉
功能性鼻内镜手术
术腔粘连
鼻用糖皮质激素
Bioabsorbable corticosteroid-eluting sinus stents
Chronic rhinosinusitis
Nasal polyps
Functional endoscopic sinus surgery
Cavity adhesion
Nasal glucocorticoids
