摘要
目的探讨(18)^F-氟代脱氧葡萄糖正电子发射计算机体层显像((18)^F-FDGPET/CT)对原发性肺癌术前纵隔淋巴结N分期的诊断价值。方法收集经病理检查确诊的92例原发性肺癌患者的病历资料,所有患者术前均进行(18)^F-FDGPET/CT和CT检查。以病理结果为金标准,比较(18)^F-FDGPET/CT和CT诊断原发性肺癌的符合率,并分析PET/CT诊断原发性肺癌术前纵隔淋巴结N分期的准确率。结果92例原发性肺癌中,经CT检出78例,诊断符合率为84.78%;经PET/CT检出87例,诊断符合率为94.57%。PET/CT诊断肺癌的符合率高于CT(P﹤0.05)。PET/CT对原发性肺癌N_(0)期的诊断准确率为96.97%,对N_(1)期的诊断准确率为90.00%,对N_(2)期的诊断准确率为92.86%,对N_(3)期的诊断准确率为90.91%,对N分期的诊断准确率为93.48%。结论(18)^F-FDGPET/CT对原发性肺癌具有较高的诊断价值,且对术前纵隔淋巴结N分期的诊断准确率较高,可为临床制订合理的治疗方法提供可靠依据。
Objective To investigate the diagnostic value of (18)^F-fluorodeoxyglucose position emission tomography/computer tomography((18)^F-FDG PET/CT)in mediastinal lymph node N staging of primary lung cancer before surgery.Method The clinical data of 92 patients with primary lung cancer confirmed by pathology were collected.All patients received (18)^F-FDG PET/CT and CT examination before surgery.By using pathological results as the gold standard,the coincidence rate of (18)^F-FDG PET/CT and CT in diagnosing primary lung cancer was compared,and the accuracy of PET/CT in evaluating preoperative N staging of the mediastinal lymph nodes of primary lung cancer was analyzed.Result A total of 78 and 87 cases in 92 cases with primary lung cancer were detected by CT and PET/CT,respectively,and the diagnostic coincidence rate of PET/CT was higher than that of CT(94.57%vs 84.78%,P<0.05).The diagnostic accuracy of PET/CT for N_(0) stage was 96.98%,N_(1) stage 90.00%,N_(2) stage 92.86%,and N_(3) stage 90.91%.For N staging,the overall diagnostic accuracy was 93.48%.Conclusion (18)^F-FDG PET/CT has higher diagnostic value in primary lung cancer and higher diagnostic accuracy for preoperative mediastinal lymph node N staging,which can be used to provide reliable evidence for reasonable treatment.
作者
张建伟
王洪伟
许科
张杰
ZHANG Jianwei;WANG Hongwei;XU Ke;ZHANG Jie(Department of Nuclear Medicine,Zhumadian Central Hospital,Zhumadian 463000,He’nan,China;Department of Radiotherapy,Zhumadian Central Hospital,Zhumadian 463000,He’nan,China;Department of Nuclear Medicine,He’nan Provincial People’s Hospital,Zhengzhou 450000,He’nan,China)
出处
《癌症进展》
2022年第6期592-594,615,共4页
Oncology Progress
