摘要
目的:研究电针八髎穴配合穴位注射鼠神经生长因子(mNGF)治疗脊髓损伤(SCI)后神经源性膀胱(NB)功能障碍的临床效果。方法:60例SCI后NB尿潴留型患者,用随机数字分配法分为两组,普通电针刺组(对照组)及电针联合穴位注射mNGF组(观察组);两组同时治疗4个疗程后评估膀胱功能积分、排尿情况、生活质量、中医证候评分以及对残余尿量(RUV)和膀胱压力、尿流速率的测定。结果:与对照组比较,观察组治疗后膀胱功能积分、日均排尿次数、残余尿量、中医证候等各维度的评分均显著下降,而排尿情况中日均单次排尿、膀胱压力容积、膀胱排尿压力、尿流速率、下尿路症状(LUTS)及生活质量评分均提高,差异有统计学意义(P<0.05)。结论:电针八髎穴联合mNGF穴位注射对SCI后NB排尿功能重建有较好效果。
Objective:To study the clinical effect of electroacupuncture at Baliao point combined with acupoint injection of mouse nerve growth factor(mNGF)on the improvement of neurogenic bladder(NB)dysfunction after spinal cord injury(SCI).Methods:A total of 60 patients with NB urinary retention after SCI who were qualified according to the inclusion criteria were randomly divided into two groups:ordinary electroacupuncture group(control group)and electroacupuncture combined with acupoint injection of mNGF group(observation group).The bladder function score,urination diary,quality of life,TCM syndrome score,residual urine volume(RUV),bladder pressure and urinary flow rate were evaluated after four courses of treatment.Results:After treatment,the scores of bladder function score,average daily micturition times,residual urine volume and TCM syndrome decreased significantly,while the scores of daily single micturition,bladder pressure volume,bladder micturition pressure,urinary flow rate,LUTS and quality of life in micturition diary increased significantly(P<0.05).Conclusion:Electroacupuncture at Baliao point combined with mNGF point injection has a good effect on the reconstruction of NB micturition function after SCI.
作者
柳珺桐
丁天红
张润宁
梁风俊
张荣荣
申艳方
LIU Juntong;DING Tianhong;ZHANG Running;LIANG Fengjun;ZHANG Rongrong;SHEN Yanfang(Xi’an Medical College,Xi’an 710021,China)
出处
《陕西中医》
CAS
2022年第5期653-657,共5页
Shaanxi Journal of Traditional Chinese Medicine
基金
陕西省科技厅重点研发科研项目(2017SF-304)
陕西省咸阳市科技局科研项目(2017K02-78)。
关键词
脊髓损伤
神经源性膀胱
电针
穴位注射
八髎穴
Spinal cord injury
Neurogenic bladder
Electroacupuncture
Acupoint injection
Baliao point
