摘要
以色酮-3-甲醛和3-氨基吡唑为原料,通过一锅法缩合反应得到新型猝灭型席夫碱荧光探针Z。在V(DMSO)∶V(H_(2)O)=3∶2的溶液中,通过选择性、灵敏度、抗干扰、稳定性及pH影响等实验,证实该探针具有较好的稳定性,能够高灵敏度和选择性地识别CN^(-),最低检测限为1.9×10^(-8)mol/L。进一步荧光滴定实验和机理研究,推测探针Z对CN^(-)的识别为加成反应型,结合比为1∶1,结合常数为0.4×10^(3)L/mol。探针Z具有较好实用性,能够方便地用于苦杏仁中CN^(-)定性检测。
A novel fluorescence quenching Schiff base probe Z was synthesized by one pot condensation reaction of chromone-3-formaldehyde and 3-aminopyrazole.In a solution of V(DMSO)∶V(H_(2)O)=3∶2,the selectivity,sensitivity,anti-interference,stability and pH effect experiments showed that the probe had good stability.It can identify CN^(-)with high sensitivity and selectivity,and its minimum detection limit is 1.9×10^(-8)mol/L.Further fluorescence titration experiment and mechanism study speculated that probe Z for CN^(-)recognition goes through an addition reaction type,its binding ratio and binding constant is 1∶1 and 0.4×10^(3)L/mol,respectively.Probe Z has good practicability and can be easily used for the qualitative determination of CN^(-)in bitter almond.
作者
赵俊
蔡小华
ZHAO Jun;CAI Xiao-hua(School of Chemical Engineering,Guizhou Minzu University,Guiyang 550025,China)
出处
《化学试剂》
CAS
北大核心
2022年第5期724-728,共5页
Chemical Reagents
基金
贵州省科技计划项目([2018]1077)。
