摘要
目的评估非手术方式于不同时机矫正先天性耳郭畸形的有效性和安全性。方法检索Cochrane Library、PubMed、Medline、中国知网、维普、万方数据库,搜集有关非手术方式矫正小儿先天性耳畸形的文献,检索时间均为建库至2021年5月,提取资料后用RevMan 5.3软件进行统计分析。结果最终纳入15项研究,共1349例患者,其中观察组(年龄<6周)669例,对照组(年龄>6周)680例。Meta分析结果显示,观察组年龄<6周开始非手术矫正比对照组明显提高矫正显效率,OR=4.67,95%CI为3.21,6.78,Z=8.09,P<0.001。观察组年龄<6周开始非手术矫正并发症低于对照组,OR=0.27,95%CI为0.08,0.88,Z=2.18,P=0.03。观察组年龄<6周开始矫正比对照组所需矫正时间短,MD=-11.81,95%CI为-18.36,-5.26,Z=3.54,P=0.001。结论先天性耳畸形患儿在<6周接受非手术矫正有更好的疗效和安全性。
Objective To evaluate the efficacy and safety of nonsurgical methods in early postnatal correction of congenital auricle malformation.Methods The clinical trials regarding non-surgical treatment for congenital ear deformity published before May 2021 were searched in databases of Cochrane Library,PubMed,Medline,CNKI,VIP and Wanfang.The information of included studies was extracted.The Meta-analysis was performed by using RevMan 5.3 software.Results A total of 15 trials were included,involving 1349 patients.The Meta-analysis results showed that the effect of the group<6 weeks was better than the group over 6 weeks(OR=4.67,95%CI:3.21,6.78,Z=8.09,P<0.001);The complications incidence of the group<6 weeks was lower than the group over 6 weeks(OR=0.27,95%CI:0.08,0.88,Z=2.18,P=0.03);The correction time required of the group<6 weeks was shorter than the group over 6 weeks(MD=-11.81,95%CI:-18.36,-5.26,Z=3.54,P=0.001).Conclusions Non-surgical correction of congenital ear malformation within 6 weeks after birth has better efficacy and safety.
作者
徐伟力
周玥
蒋宙男
戚吉妮
李金晟
张菊芳
Xu Weili;Zhou Yue;Jiang Zhounan;Qi Jini;Li Jinsheng;Zhang Jufang(The Fourth Clinical Medical College of Zhejiang Chinese Medical University,Hangzhou 310053,China;Nanjing Medical University,Nanjing 211100,China;Department of Plastic Surgery,Hangzhou First People's Hospital,Zhejiang University Medical College,Hangzhou 310006,China)
出处
《中华医学美学美容杂志》
2022年第2期119-122,共4页
Chinese Journal of Medical Aesthetics and Cosmetology
关键词
耳郭
先天性耳郭畸形
矫正时机
专题Meta分析
非手术治疗
Auricle
Congenital auricular deformities
Treatment timing
Meta-analysis
Non-surgical correction
