摘要
氟哌噻吨美利曲辛导致的迟发性运动障碍(tardive dyskinesia,TD)少见文献报告。本文报告1例高龄女性混合性焦虑抑郁障碍患者,服用氟哌噻吨美利曲辛1年后,出现不自主口-舌-颊动作,异常不自主运动量表(abnormal involuntary movement scale,AIMS)评分为12分,诊断为TD,停用氟哌噻吨美利曲辛,未作其它处理。停药后TD症状在短暂加重后逐渐减轻,1年后完全消除,再评AIMS为0分。其转归较为特殊,有别于以往关于TD“不可逆”的普遍认识,值得同行关注和讨论。
Tardive dyskinesia(TD)caused by Flupentixol and Melitracen was rarely reported in the literature.This paper reports a case of elderly female patient with anxiety and depression,who developed involuntary movement of mouth,tongue and cheek after taking Flupentixol and Melitracen tablets for one year.The score of abnormal involuntary movement scale(AIMS)was 12.Flupentixol and Melitracen was stopped immediately since she was diagnosed as tardive dyskinesia(TD)and no other treatment was given for TD.After drug withdrawal,the TD symptoms were gradually alleviated after a brief aggravation,and completely eliminated after 1 year.The reevaluation of AIMS was 0.Given the reversible nature of her condition,which is different from previous consensus on"irreversibility"of TD,this case is worthy of peer attention and discussion.
作者
吴菲
张莹洁
徐佳
WU Fei;ZHANG Yingjie;XU Jia(Department of psychiatry,Tsinghua University Hospital,Beijing 100084,China)
出处
《中国神经精神疾病杂志》
CAS
CSCD
北大核心
2022年第2期109-111,共3页
Chinese Journal of Nervous and Mental Diseases
关键词
迟发性运动障碍
可逆
氟哌噻吨美利曲辛
锥体外系反应
异常不自主运动量表
不自主运动
转归
Delayed dyskinesia(TD)
Reversible
Flupentixol and melitracen
Extrapyramidal reactions abnormalinvoluntarymovementscale(AIMS)
Involuntary movement
Outcome
