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两种四联方案根治幽门螺杆菌的疗效比较 被引量:2

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摘要 幽门螺杆菌(helicobacter pylori,HP)是唯一能在胃内强酸环境中长时间存活的致病菌,与慢性胃炎、消化性溃疡、胃黏膜相关的淋巴瘤、消化道肿瘤等多种消化道疾病密切相关[1],是胃癌的独立危险因素。目前,我国居民HP感染率超过50%[2],根除HP的方案已从传统和标准的三联疗法发展至四联疗法。根据《第五次全国幽门螺杆菌感染处理共识报告》,HP对多种抗生素产生耐药,严重影响根治率[3-4]。由于HP的根治效果与HP感染相关性疾病的治疗效果密切相关,笔者临床发现许多HP感染患者在中青年时期即出现严重的胃黏膜萎缩现象,考虑与幼年感染HP相关,因此根治HP至关重要。该文旨在比较常用的两种抗HP四联方案的治疗效果及不良反应,现报道如下。
出处 《浙江临床医学》 2022年第4期609-610,共2页 Zhejiang Clinical Medical Journal
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