摘要
目的评价麻醉诱导前进行经皮穴位电刺激(TEAS)对全麻手术术后镇痛效果的影响。方法检索ScienceDirect、Pubmed、Cochrane library、Web of Science、Embase、知网、万方、维普、中国生物医学数据库等数据库,检索时间为建库至2021年11月。收集麻醉诱导前采用TEAS用于术后辅助镇痛的随机对照试验(RCT)。RevMan 5.3软件进行Meta分析。结果共纳入10篇文献,820例患者,其中TEAS组409例,对照组411例。Meta分析显示,TEAS组术后4、12、24、48 h VAS疼痛评分明显低于对照组(术后4 h,MD=-1.45分,95%CI-2.69~-0.20,P=0.02;术后12 h,MD=-0.50分,95%CI-0.98~-0.02,P=0.04;术后24 h,MD=-0.75分,95%CI-1.10~-0.40,P<0.01;术后48 h,MD=0.38分,95%CI-0.74~-0.02,P=0.04),术后恶心呕吐发生率明显低于对照组(OR=0.35,95%CI 0.24~0.51,P<0.01),两组术中阿片类药物用量差异无统计学意义。结论麻醉诱导前应用经皮穴位电刺激可显著提高术后镇痛的效果,降低术后不良反应发生率。
Objective To evaluate the effect of transcutaneous electrical acupoint stimulation(TEAS)before anesthesia induction on postoperative analgesia in general anesthesia operation.Methods The database was searched from ScienceDirect,Pubmed,Cochrane Library,Web of Science,Embase,CNKI,Wanfang,VIP,and Chinese Biomedical Database from the establishment of the database to November 2021.Randomized controlled trials(RCT)on applying TEAS before anesthesia induction to postoperative analgesia were collected.All data were extracted for statistical analysis by using RevMan 5.3 software.Results A total of 820 patients were included in 10 references,including 409 in the TEAS group and 411 in control group.Meta-analysis showed that,compared with control group,VAS pain score were significantly lower at 4,12,24 and 48 hours after surgery in the TEAS group(4 hours after surgery,MD=-1.45,95%CI-2.69 to-0.20,P=0.02;12 hours after surgery,MD=-0.50,95%CI-0.98 to-0.02,P=0.04;24 hours after surgery,MD=-0.75,95%CI-1.10 to-0.40,P<0.01;48 hours after surgery,MD=0.38,95%CI-0.74 to-0.02,P=0.04),and the incidence of postoperative nausea and vomiting were significantly reduced in the TEAS group(OR=0.35,95%CI 0.24 to 0.51,P<0.01).There was no statistically significant difference in intraoperative opioid dosage between the two groups.Conclusion Using Transcutaneous electrical acupoint stimulation before anesthesia induction can significantly improve the efficacy of postoperative analgesia,reduce the incidence of postoperative adverse reactions.
作者
任善洁
鹿洪秀
张栋斌
苏帆
REN Shanjie;LU Hongxiu;ZHANG Dongbin;SU Fan(The First Clinical Medical College of Shandong University of Traditional Chinese Medicine,Jinan 250355,China)
出处
《临床麻醉学杂志》
CAS
CSCD
北大核心
2022年第4期400-405,共6页
Journal of Clinical Anesthesiology
关键词
经皮穴位电刺激
术后镇痛
不良反应
META分析
Transcutaneous electrical acupoint stimulation
Postoperative analgesia
Adverse reactions
Meta-analysis