摘要
目的探讨帕金森病(PD)患者危险因素。方法选取本院2015年1月至2018年12月PD患者90例作为PD组,另按照1∶1的比例选取同期同科室就诊的其他疾病患者90例作为非PD组,分析影响PD发生的危险因素。结果在婚状态、存在饮酒史人群PD发生率与其他人群比较差异无统计学意义(P>0.05);农民、杀虫剂接触史人群PD发生率高于其他职业人群,受教育程度较高、进行规律的体育锻炼、参与户外娱乐活动、饮茶、经常进行阅读和写作人群PD发生率低于其他人群,差异有统计学意义(P<0.05);Logisitic回归分析显示职业、杀虫剂接触史是PD发生的独立危险因素,受教育程度高、规律的体育锻炼、积极参与户外娱乐活动、饮茶、经常进行阅读与写作是PD发生的保护因素。结论筛查PD发生的相关影响因素对于开展PD的预防具有一定程度的指导意义,有利于延缓PD发生进展。
Objective To explore the risk factors in patients with Parkinson’s disease(PD).Methods A total of 90 patients with PD in the hospital were enrolled as PD group between January 2015 and December 2018,while other 90 patients with other diseases treated in the same department during the same period were enrolled as non-PD group.The risk factors of PD were analyzed.Results There was no significant difference in the incidence of PD between people with marriage status and drinking history and the others(P>0.05).The incidence of PD in farmers and people with history of pesticide exposure was higher than that in the others,and incidence of PD in people with high education level,regular physical exercise,participation in outdoor recreational activities,drinking tea,frequent reading and writing was lower than that in the others(P<0.05).Logisitic regression analysis showed that occupation and history of pesticide exposure were independent risk factors of PD,while high education level,regular physical exercise,active participation in outdoor recreational activities,drinking tea,frequent reading and writing were protective factors.Conclusion Screening the influencing factors of PD is of certain guidance significance for PD prevention,which is beneficial to delay the development of PD.
作者
黄荣
李晓晖
陈文武
HUANG Rong;LI Xiao-hui;CHEN Wen-wu(The Second Ward,Department of Neurology,the First Affiliated Hospital of Henan University,Kaifeng 475000,Henan Province,China)
出处
《罕少疾病杂志》
2022年第6期17-19,共3页
Journal of Rare and Uncommon Diseases
关键词
帕金森病
临床资料
危险因素
Parkinson’s Disease
Clinical Data
Risk Factor
