摘要
目的探讨不同年龄段肺血栓栓塞症(PTE)患者的临床特征及疗效。方法收集2016年3月至2020年12月于山西白求恩医院急诊及门诊就诊的287例PTE患者的临床资料。根据年龄不同将患者分为老年组(n=126,≥65岁)和非老年组(n=161,<65岁)。记录两组患者的基础疾病情况、临床症状及体征。观察两组患者的临床疗效。观察两组患者治疗期间的并发症发生情况,并发症包括右心衰竭、肺动脉高压、心肌缺血和心源性休克。结果老年组中有肢体制动或卧床史、手术及外伤史、慢性阻塞性肺疾病、冠心病、高血压、糖尿病、慢性肾脏病、心房颤动、脑梗死病史的患者比例均高于非老年组,差异均有统计学意义(P<0.05)。老年组患者胸闷、咳嗽及咳痰、肺部啰音的发生率均高于非老年组,呼吸困难、胸痛、咯血的发生率均低于非老年组患者,差异均有统计学意义(P<0.05)。两组患者下肢肿胀、晕厥的发生率比较,差异均无统计学意义(P>0.05)。治疗后,两组患者的症状、体征均好转。两组患者均发生了右心衰竭、肺动脉高压、心肌缺血和心源性休克。结论不同年龄段PTE患者的临床特征存在差异,临床上需早期识别,区别对待,降低病死率及并发症发生率。
Objective To investigate the clinical features and efficacy of pulmonary thromboembolism(PTE)patients in different age groups.Method The clinical data of 287 PTE patients who visited the emergency department and outpatient clinic of Shanxi Bethune Hospital from March 2016 to December 2020 were collected.The patients were divided into an elderly group(n=126,≥65 years old)and a non-elderly group(n=161,<65 years old)according to their age distribution.The basic diseases,clinical symptoms and signs of the two groups were recorded.The clinical effects of the two groups were observed.The complications of the two groups during treatment were observed,including right heart failure,pulmonary hypertension,myocardial ischemia and cardiogenic shock.Result The proportion of patients with the history of limb immobilization or bed rest,history of surgery and trauma,chronic obstructive pulmonary disease,coronary heart disease,hypertension,diabetes,chronic kidney disease,atrial fibrillation,and cerebral infarction in the elderly group was higher than that in the non-elderly group,the differences were statistically significant(P<0.05).The incidences of chest tightness,cough,expectoration,and pulmonary rales in the elderly group were higher than those in the non-elderly group,and the incidences of dyspnea,chest pain,and hemoptysis were lower than those in the non-elderly group,and the differences were statistically significant(P<0.05).There was no significant difference in the incidence of lower extremity swelling and syncope between the two groups(P>0.05).After the treatment,the symptoms and signs of the two groups were improved.Right heart failure,pulmonary hypertension,myocardial ischemia,and cardiogenic shock were reported in both groups.Conclusion There are differences in the clinical characteristics of PTE patients in different age groups.Therefore,it is necessary to identify these differences early in clinical practice and treat them according to their condition,thus reducing the mortality and complication rates.
作者
张克
杨涛
续慧民
张建陶
郝斌
Zhang Ke;Yang Tao;Xu Huimin;Zhang Jiantao;Hao Bin(Department of Vascular Surgery,Shanxi Bethune Hospital,Shanxi Academy of Medical Sciences,Tongji Shanxi Hospital,Third Hospital of Shanxi Medical University,Taiyuan 030032,Shanxi,China)
出处
《血管与腔内血管外科杂志》
2022年第3期275-278,308,共5页
Journal of Vascular and Endovascular Surgery
基金
山西省重点研发计划项目(201903D321154)。
关键词
肺血栓栓塞症
年龄
临床特征
疗效
并发症
pulmonary thromboembolism
age
clinical feature
effect
complication
