摘要
目的分析胫腓骨骨折术后采用自拟活血消肿止痛方治疗对患者应激反应、术后疼痛、骨折愈合效果影响。方法选取2019年1月至2021年1月在长沙市中医院手术治疗的100例胫腓骨骨折患者进行研究,按照随机数字表法进行分组,每组各50例,对照组给予术后常规治疗,在此基础上,观察组给予自拟活血消肿止痛方治疗。比较两组手术前后应激反应、术后疼痛肿胀情况、骨折愈合效果等。结果观察组术后各时间视觉模拟评分(VAS)低于对照组,差异有统计学意义(P<0.05);治疗结束时,观察组应激指标丙二醛(MDA)、超氧化物歧化酶(SOD)、去甲肾上腺素(NE)、皮质醇(COR)水平均低于对照组,差异有统计学意义(P<0.05);观察组骨折愈合优良率为90.00%,高于对照组的60.00%,差异有统计学意义(P<0.05);术后10 d,观察组肿胀Ⅰ度占76.00%、Ⅱ度占22.00%、Ⅲ度占2.00%,对照组分别占40.00%、54.00%、6.00%,两组的肿胀程度明显减轻,与术后1 d比较差异有统计学意义(P<0.05),观察组肿胀缓解程度明显优于对照组,差异有统计学意义(P<0.05)。结论自拟活血消肿止痛方能够有效降低胫腓骨骨折手术患者的应激反应水平,减轻患者术后疼痛、肿胀程度,有利于促进骨折愈合,具有重要的研究价值。
Objective To analyze the effect of self-prepared Huoxue Xiaozhong Zhitong(blood-activating,swelling-dispersing and pain-relieving)prescription on stress response,postoperative pain and fracture healing effect for patients undergoing tibia and fibular fracture surgery.Methods A total of 100 patients with tibia and fibular fractures treated surgically in Changsha Hospital of Traditional Chinese Medicine from January 2019 to January 2021 were selected as study subjects,and grouped according to the random number table method,with 50 patients in each group.The control group was given postoperative conventional treatment,and the observation group was given the self-prepared Huoxue Xiaozhong Zhitong prescription on the basis of the treatment in the control group.The postoperative stress response,postoperative pain and swelling,and fracture healing effect were compared between the two groups before and after surgery.Results The postoperative visual analogue scale(VAS)scores of the observation group were lower than those of the control group,with statistically significant differences(P<0.05).After the end of treatment,the levels of stress response indicators such as malondialdehyde(MDA),superoxide dismutase(SOD),norepinephrine(NE),and cortisol(COR)in the observation group were lower than those in the control group,with statistically significant differences(P<0.05).The excellent rate of fracture healing in the observation group(90%)was higher than that in the control group(60%),with statistically significant differences(P<0.05).At 10 d after surgery,76.00%of patients were in swelling degreeⅠ,22.00%in degreeⅡ,and 2.00%in degreeⅢin the observation group,and 40.00%,54.00%,and 6.00%in the control group,respectively,showing a significant reduction in swelling degree in both groups,with statistically significant differences from those at 1 d after surgery(P<0.05),and the degree of swelling relief in the observation group was significantly higher than that in the control group,with statistically significant differences(P<0.05).Conclusion Self-prepared Huoxue Xiaozhong Zhitong prescription can effectively reduce the level of stress response,relieve postoperative pain and swelling,and promote fracture healing in patients with tibia and fibular fracture surgery,which is of i mportant research value.
作者
王光辉
WANG Guanghui(Second Disease Area of the Department of Orthopedics,Changsha Hospital of Traditional Chinese Medicine,Hunan,Changsha 410000,China)
出处
《中国医药科学》
2022年第9期94-97,122,共5页
China Medicine And Pharmacy
关键词
胫腓骨骨折手术
活血消肿止痛方
术后疼痛
骨折愈合
Tibia and fibular fracture surgery
Huoxue Xiaozhong Zhitong prescription
Postoperative pain
Fracture healing
