摘要
目的 分析内镜经鼻修补手术治疗非肿瘤性脑脊液鼻漏的效果和影响并发症的危险因素。方法 回顾2011年6月~2021年6月就诊于首都医科大学宣武医院的114例非肿瘤性脑脊液鼻漏患者行内镜经鼻脑脊液鼻漏修补术的治疗结果,采用多因素Logistic回归对并发症的影响因素进行统计分析。结果 110例患者一次修补成功。4例患者一期手术失败,其中3例行二次修补,1例行脑室腹腔分流术,均获得成功。在随访6个月~10年中,2例患者复发,再次修补获得成功。回归分析显示,术前脑膜炎的病史明显增加了术后颅内感染的风险(OR=24.324,95%CI 2.994~197.599)。结论 对于非肿瘤性脑脊液鼻漏的患者,内镜经鼻手术可获得较为理想的长期效果。术前脑膜炎史是患者术后颅内感染的独立危险因素。
OBJECTIVE To evaluate the efficacy of endoscopic endonasal reconstruction for nonneoplastic cerbrospinal fluid(CSF) rhinorrhea and the risk factors of surgical complication.METHODS Data of 114 patients with nonneoplastic CSF rhinorrhea who admitted to Xuanwu Hospita1,Capital Medical University and repaired via endoscopic endonasal approach between June 2011 and June 2021 were analyzed retrospectively.Multivariate Logistic regression analysis was conducted to summarize the risk factors of postoperative complications.RESULTS There were 110 patients cured by primary reconstruction successfully,and 4 patients cured after second surgery,which included three second repair and one ventriculoperitoneal shunt.Being followed up for 6 months to 10 years,Two patients relapsed and cured after second repair.Regression analysis showed that previous meningitis obviously elevated the risk of postoperative intracranial infection(OR=24.324,95%CI 2.994-197.599).CONCLUSIONFor the patients with nonneoplastic CSF rhinorrhea,endoscopic endonasal reconstruction can achieve optimal long-term outcome.Previous meningitis was an independent risk factor of the postoperative intracranial infection.
作者
危维
刘俊其
杨晓彤
齐岩
严波
王振霖
张秋航
WEI Wei;LIU Junqi;YANG Xiaotong;QI Yan;YAN Bo;WANG Zhenlin;ZHANG Qiuhang(Department of Otolaryngology Head and Neck Surgery,Xuanwu Hospital,Capital Medical University,Beijing,100053,China)
出处
《中国耳鼻咽喉头颈外科》
CSCD
2022年第4期221-224,共4页
Chinese Archives of Otolaryngology-Head and Neck Surgery
关键词
脑脊液鼻漏
内窥镜检查
Cerebrospinal Fluid Rhinorrhea
Endoscopy
