摘要
鞭毛是着生在很多细菌体表的细长弯曲丝状物,作为细菌的运动“器官”,鞭毛是微生物学中研究最深入的生理系统之一。细菌可以通过鞭毛运动更好地适应栖息环境,并在环境条件不利时及时逃离。此外,鞭毛运动对于有害细菌或者有益细菌在宿主表面的定殖、生物膜形成及其与宿主其他互作过程中都发挥着重要作用。芽孢杆菌(Bacillus sp.)是一类在自然界中广泛分布的细菌,其许多菌株在工农业生产及医药等领域都有重要的应用价值,本文对芽孢杆菌鞭毛及其运动相关特性的研究进展进行了综述:芽孢杆菌鞭毛的结构组成、组装过程及合成基因的表达调控;芽孢杆菌运动性与相关生物学特性,包括生物膜形成和分散、芽孢的形成、感受态形成、γ-聚谷氨酸和抗生素生产等方面之间的相互关系及其底层分子机制。本综述旨在为本领域的相关研究提供可参考的综合知识和理论指导依据。
Flagella are slender and curved protein filaments associated with the surface of many bacteria.As the motility‘organ’of bacteria,flagellum is one of structures that have been most extensively studied in microbiology.Through flagellar movement,bacteria can better adapt to their habitat or escape from unfavorable environments.In addition,flagellar plays an important role in the colonization of host surfaces by harmful or beneficial bacteria,and in their biofilm formation and other tight interaction with their hosts.Bacillus is ubiquitous in the nature containing many species and strains with great value in industrial,agricultural and medicinal applications.In this work,the research progress on the flagella and motility-related properties of Bacillus is reviewed.Firstly,we introduced the structural composition,assembly process,and expression regulation of synthetic genes of Bacillus flagella.Secondly,relationships and the underlying molecular mechanisms of Bacillus flagella motility and its motility-related characteristics of including the biofilm formation and dispersal,sporulation,competence,and production ofγ-polyglutamic acid and antibiotics is discussed.This review aims at providing comprehensive knowledge and theoretical guidance for related studies in this field.
作者
范萌
黄升泉
李昱龙
赵银娟
樊奔
FAN Meng;HUANG Shengquan;LI Yulong;ZHAO Yinjuan;FAN Ben(College of Biology and Environment,Nanjing Forestry University,Nanjing 210037,Jiangsu,China;College of Forestry,Nanjing Forestry University,Nanjing 210037,Jiangsu,China)
出处
《微生物学通报》
CAS
CSCD
北大核心
2022年第5期1832-1845,共14页
Microbiology China
基金
国家自然科学基金(31970097)。
