摘要
目的:对本院2020年急诊就诊患者静脉应用糖皮质激素(glucocorticoids,GCs)的处方进行分析,以期为医疗机构对该类药物在急诊中的临床管理提供依据。方法:回顾性选取本院2020年1月1日~12月31日64069张急诊处方,其中含静脉应用GCs药物的处方713张。对患者一般信息、药品名称、用法用量、联合用药、临床诊断等进行分类统计分析。结果:在713张含静脉应用GCs药物的处方中,患者以18~39岁的青壮年为主。最常用的静脉应用GCs药物是甲泼尼龙(66.06%),其次为地塞米松(33.38%)。疾病类型主要为过敏相关急症(291例,40.81%)、感染类疾病(158例,22.16%)、呼吸系统疾病(137例,19.21%)等。713张处方中,用药不合理处方共12张(1.68%),主要为无适应症用药。结论:本院急诊静脉应用GCs药物的处方总体较为合理,但仍存在少数用药指征不明的情况。药师应熟悉并不断更新临床知识与各科指南,提高医嘱审核能力,及时干预不合理处方,为医疗机构进一步改善GCs药物不合理应用现象提供临床依据。
Objective:To analyze the prescriptions of intravenous glucocorticoids(GCs)in emergency patients in our hospital in 2020,in order to provide a basis for the clinical management of these drugs in emergency patients by medical institutions.Methods:A total of 713 prescriptions containing GCs were extracted from 64069 emergency prescriptions from January 1 to December 31,2020 in our hospital were retrospectively selected,and the general information of patients,drug name,usage and dosage,combined medication,clinical diagnosis,etc.were analyzed by classification and statistics.Results:Among the 713 prescriptions containing GCs,the patients were mainly young adults aged 18~39.The most commonly used GCs were methylprednisolone(66.06%)and dexamethasone(33.38%).The types of diseases are mainly divided into allergy-related emergencies(291 cases,accounting for 40.81%),infectious diseases(158 cases,accounting for 22.16%),and respiratory diseases(137 cases,accounting for 19.21%),etc.Among 713 prescriptions,12 prescriptions were unreasonable,accounting for 1.68%,mainly off-label medication.Conclusion:The prescription of intravenous GCs drugs in the emergency department of our hospital is generally reasonable,but there are still a few cases with unclear drug indications.Pharmacists should be familiar with and constantly update clinical knowledge and guidelines of various departments,improve the review ability of doctor’s order,and intervene in unreasonable prescriptions in time,to provide clinical basis for medical institutions to further improve the unreasonable application of GCs.
作者
任燕
杜倩
苟静惠
戴黎阳
卜鑫珏
REN Yan;DU Qian;GOU Jing-hui;DAI Li-yang;BU Xin-jue(Department of Pharmacy,the Third Affiliated Hospital of Chongqing Medical University,Chongqing 401120,China)
出处
《中国合理用药探索》
2022年第4期26-31,共6页
Chinese Journal of Rational Drug Use
关键词
急诊
糖皮质激素
静脉应用
用药分析
药事管理
处方
emergency
glucocorticoid
intravenous
drug analysis
pharmacy management
prescriptions
