摘要
目的 观察治疗成人支气管哮喘急性发作期联用溴化异丙托品及沙丁胺醇雾化吸入的临床治疗效果。方法 回顾性分析2019年3月至2020年1月辽宁省健康产业集团铁煤总医院收治的78例支气管哮喘急性发作期成人患者,依据治疗方法将其分为对照组和观察组,每组各39例。对照组采用溴化异丙托品雾化吸入治疗,观察组患者在对照组基础上联合沙丁胺醇雾化吸入疗法,比较两组的疗效、症状缓解时间、动脉血气指标变化情况及哮喘症状控制(ACT)评分。结果 观察组的总有效率为94.87%,高于对照组的79.49%,差异有统计学意义(P<0.05);观察组的胸闷、气促、咳嗽、喘鸣症状缓解时间均短于对照组,差异有统计学意义(P<0.05);治疗后,观察组的动脉血气指标水平均高于对照组,ACT症状评分低于对照组,差异有统计学意义(P<0.05)。结论 溴化异丙托品联合沙丁胺醇雾化吸入治疗成人支气管哮喘急性发作期,疗效理想,可以缩短症状改善时间,值得推广应用。
Objective To observe the clinical efficacy of ipratropium bromide combined with salbutamol aerosol inhalation in the treatment of acute attack of adult bronchial asthma. Methods A total of 78 cases of adult patients with acute attack of bronchial asthma admitted to and treated in Tiemei General Hospital of Liaoning Health Industry Group from March 2019 to January 2020 were retrospectively analyzed. According to the treatment methods, they were divided into the control group(n=39) and the observation group(n=39). The control group was treated with ipratropium bromide aerosol inhalation, while the observation group was treated with salbutamol aerosol inhalation on the basis of the control group. The therapeutic efficacy, symptom relief time, level changes of arterial blood gas index and symptom score of Asthma Control Test(ACT) were compared between the two groups. Results The total effective rate in the observation group was 94.87%, which was higher than 79.49% in the control group, with statistically significant difference(P<0.05).The relief time of chest tightness, shortness of breath, cough and wheezing in the observation group was shorter than that in the control group, with statistically significant differences(P<0.05). After treatment, the arterial blood gas index levels of the observation group were all higher than those of the control group, and the symptom score of ACT was lower than that of the control group, with statistically significant differences(P <0.05). Conclusion Ipratropium bromide combined with salbutamol aerosol inhalation has satisfying therapeutic efficacy in the treatment of acute attack of adult bronchial asthma, which can shorten the time of symptom improvement. Therefore, it is worthy of promotion and application.
作者
刘哲
LIU Zhe(Department of Respiratory,Tiemei General Hospital of Liaoning Health Industry Group,Tieling 112700,China)
出处
《中国现代医生》
2022年第15期96-99,共4页
China Modern Doctor
