摘要
目的探讨温肾排石汤联合康复干预对复杂性肾结石术后患者肾功能及炎症反应的影响。方法选择108例复杂性肾结石患者,随机分为研究组与对照组,各54例。对照组予经皮肾镜碎石取石术联合常规治疗,研究组在经皮肾镜碎石取石术后予温肾排石汤进行治疗。2组治疗周期均为2周,治疗期间均予康复干预。比较2组治疗后的疗效,治疗前后中医证候积分、肾功能及血清炎性因子水平。结果治疗后,研究组总有效率(92.59%,50/54)高于对照组(75.93%,41/54)(P<0.05)。与治疗前比较,治疗后,2组舌苔腻质暗黄、腰腹部疼痛、血尿或尿色赤黄、排尿涩痛、排尿中断评分、总分、血清肌酐(SCr)、胱抑素C(Cys-C)、尿素氮(BUN)、高迁移率族蛋白B1(HMGB1)、单核细胞趋化蛋白-1(MCP-1)及超敏C反应蛋白(hs-CRP)水平均降低,研究组低于对照组(P<0.05)。结论温肾排石汤联合康复干预可明显改善复杂性肾结石术后患者的中医证候及肾功能,减轻机体炎症反应,有助于提高疗效。
Objective To investigate the effect of Wenshen Paishi Decoction combined with a rehabilitation intervention on the renal function and inflammatory reactions in patients with complicated nephrolithiasis after operation.Methods A total of 108 patients with complicated nephrolithiasis were selected as the research subjects and randomly divided into a study group and a control group,54 cases in each group.The control group was treated with percutaneous nephrolithotomy combined with a conventional treatment,while the study group was treated with Wenshen Paishi Decoction after percutaneous nephrolithotomy.The treatment period of both groups was two weeks,and both groups were given a rehabilitation intervention during treatment.The curative effect after treatment,TCM syndrome scores,renal function and serum inflammatory factor levels before and after treatment were compared between the two groups.Results After treatment,the total effective rate in the study group(92.59%,50/54)was higher than that in the control group(75.93%,41/54)(P<0.05).Compared with before treatment,the individual scores and total scores of greasy and dark yellow tongue coating,waist and abdomen pain,hematuria or red-yellow urine,astringent urination,urination interruption,the levels of serum creatinine(SCr),cystatin C(Cys-C),blood urea nitrogen(BUN),high mobility group protein B1(HMGB1),monocyte chemoattractant protein-1(MCP-1)and hypersensitive C-reactive protein(hs-CRP)in the two groups were decreased,and the study group was lower than the control group(P<0.05).Conclusion Wenshen Paishi Decoction combined with a rehabilitation intervention can significantly improve the TCM syndromes and renal function of patients with complicated nephrolithiasis after surgery,and can reduce the body’s inflammatory reactions,thereby helping to improve the curative effect.
作者
彭艳
赵洋
杨婵娟
高玄
PENG Yan;ZHAO Yang;YANG Chanjuan;GAO Xuan(Department of Urology,Chongqing Traditional Chinese Medicine Hospital,Chongqing 400021,China;Department of Peripheral Vascular(Wound Repair),Chongqing Traditional Chinese Medicine Hospital,Chongqing 400021,China;Department of Nursing,Chongqing Traditional Chinese Medicine Hospital,Chongqing 400021,China)
出处
《长春中医药大学学报》
2022年第6期647-650,共4页
Journal of Changchun University of Chinese Medicine
基金
2020年度“杏林学者”学科人才科研提升计划项目(YYZX2020053)。
关键词
肾结石
复杂性
温肾排石汤
康复
经皮肾镜碎石取石术
肾功能
炎症
nephrolithiasis
complicated
Wenshen Paishi Decoction
rehabilitation
percutaneous nephrolithotomy
renal function
inflammation
