摘要
目的:观察肛周脓肿术后应用痛痒消洗剂熏洗坐浴对创面愈合、肛门功能和血清炎性因子的影响。方法:全部136例肛周脓肿术术后患者均来自于我院2019年9月~2021年7月期间收治的患者。按照双色球随机分组法将患者分为对照组(68例)和研究组(68例)。对照组接受常规治疗,研究组在对照组的基础上接受痛痒消洗剂熏洗坐浴,观察两组疗效、创面愈合情况、肛门功能和血清炎性因子变化,记录两组治疗期间不良反应发生情况。结果:研究组的临床总有效率优于对照组(P<0.05)。治疗7 d后,研究组创面缩小率高于对照组,手术创面肉芽生长评分、创面疼痛程度评分低于对照组(P<0.05)。治疗3个月后,研究组肛管最大收缩压、肛管静息压大于对照组(P<0.05)。治疗7 d后,研究组血清白介素-6(IL-6)、肿瘤坏死因子-α(TNF-α)、白介素-1β(IL-1β)、白介素-8(IL-8)水平低于对照组(P<0.05)。两组均未见明显的不良反应发生。结论:肛周脓肿术后应用痛痒消洗剂熏洗坐浴,可促进创面愈合,减轻对肛门功能的损害,可能与痛痒消洗剂熏洗坐浴可有效降低血清炎性因子水平有关。
Objective: To observe the effects of hip bath fumigation with tongyangxiao lotion on wound healing, anal function and serum inflammatory factors after operation of perianal abscess. Methods: All 136 patients with perianal abscess after operation were from our hospital from September 2019 to July 2021. According to the two-color ball method, the patients were divided into control group(68cases) and study group(68 cases). The patients in the control group received routine treatment, and the study group received the hip bath fumigation with tongyangxiao lotion on the basis of the control group. The curative effect, wound healing situation, anal function and changes of serum inflammatory factors in the two groups were observed, and the adverse reactions in the two groups during the treatment were recorded. Results: The total clinical effective rate of the study group was better than that of the control group(P<0.05). 7 d after treatment, the wound reduction rate of the study group was higher than that of the control group, and the surgical wound granulation growth score and wound pain score were lower than those of the control group(P<0.05). 3 months after treatment, the maximum anal systolic pressure and anal resting pressure of the study group were higher than those of the control group(P<0.05). 7 d after treatment, the levels of serum interleukin-6(IL-6), tumor necrosis factor-α(TNF-α), interleukin-1β(IL-1β) and interleukin-8(IL-8) in the study group were lower than those of the control group(P<0.05). There were no obvious adverse reactions in both groups. Conclusion: After the operation of perianal abscess, the application of tongyangxiao lotion fumigation hip bath can promote wound healing and reduce the damage to anal function, which may be related to the fact that tongyangxiao lotion fumigation hip bath can effectively reduce the levels of serum inflammatory factors.
作者
师晨松
刘秀妃
许建成
麻倩
王佳伟
吴春晓
SHI Chen-song;LIU Xiu-fei;XU Jian-cheng;MA Qian;WANG Jia-wei;WU Chun-xiao(First Department of Anorectal,Hebei Hospital of Traditional Chinese Medicine,Shijiazhuang,Hebei,050000,China;Second Department of Anorectal,Hebei Hospital of Traditional Chinese Medicine,Shijiazhuang,Hebei,050000,China;Operation Room,Hebei Hospital of Traditional Chinese Medicine,Shijiazhuang,Hebei,050000,China)
出处
《现代生物医学进展》
CAS
2022年第7期1362-1365,1384,共5页
Progress in Modern Biomedicine
基金
河北省中医药管理局科研计划项目(2019047)。
关键词
肛周脓肿术
痛痒消洗剂
熏洗坐浴
创面愈合
肛门功能
炎性因子
Perianal abscess operation
Tongyangxiao lotion
Hip bath fumigation
Wound healing
Anal function
Inflammatory factor
