摘要
目的探讨重症脑损伤患者康复治疗早期介入的临床效果,并分析其对患者意识障碍和运动功能的影响。方法方便选择该院2018年8月—2020年9月收治的84例重症脑损伤患者作为该次研究对象,以随机数表法分为研究组和对照组,各42例,对照组实施常规药物治疗,研究组在对照组基础上早期介入康复治疗,观察两组患者治疗前后Glasgow、GMFM评分、血浆CGRP、NPY、ET-1、TNF-α水平、预后、致残及死亡情况。结果治疗后,研究组Glasgow评分(13.11±1.10)分、GMFM评分(69.21±24.69)分显著高于对照组,差异有统计学意义(t=11.872、4.381,P<0.05);研究组ET-1(64.51±4.20)pg/mL、TNF-α水平(1.58±0.11)pg/mL低于对照组,差异有统计学意义(t=2.596、5.110,P<0.05);研究组预后良好率(95.24%)高于对照组(73.81%),致残率(2.38%)低于对照组(21.43%),差异有统计学意义(χ^(2)=7.372、7.265,P<0.05),对照组病死率(4.76%)高于研究组(2.38%),差异无统计学意义(P>0.05)。结论康复治疗早期介入应用在重症脑损伤患者中的临床效果显著,可改善患者意识障碍和运动功能,提高预后良好率,值得临床进一步应用探讨。
Objective To explore the clinical effect of early intervention in rehabilitation treatment of patients with severe craniocerebral injury,and to analyze its effect on consciousness disorder and motor function.Methods 84 patients with severe brain injury treated in the hospital from August 2018 to September 2020 were selected as the study objects,and the patients were divided into study group and control group in the form of random number table.with 42 cases in each group.The control group received routine drug treatment,and the study group received early intervention rehabilitation treatment on the basis of the control group.Before and after treatment the Glasgow,GMFM scores Plasma CGRP,NPY,ET-1,NF-αlevel,prognosis,disability and death were observed.Results After treatment,Glasgow score(13.11±1.10)points and GMFM score(69.21±24.69)points in the study group were significantly higher than those in the control group,and the difference was statistically significant(t=11.872,4.381,P<0.05);ET-1(64.51±4.20)pg/mL and TNF-αlevel(1.58±0.11)pg/mL in the study group was significantly lower than that in the control group,and the difference was statistically significant(t=2.596,5.110,P<0.05);the good prognosis rate(95.24%)in the study group was higher than that in the control group(73.81%),the disability rate(2.38%)was lower than that in the control group(21.43%),the difference was statistically significant(χ^(2)=7.372,7.265,P<0.05),and the mortality rate in the control group(4.76%)was higher than that in the study group(2.38%),the difference was statistically significant(P>0.05).Conclusion The clinical effect of early intervention of rehabilitation therapy in patients with severe brain injury is significant.It can improve the patients'consciousness disorder and motor function,and improve the good prognosis rate.It is worthy of further clinical application.
作者
张振国
崔玉静
梁彬
王婧
ZHANG Zhenguo;CUI Yujing;LIANG Bin;WANG Jing(Department of Rehabilitation MedicineLiaocheng People's Hospital,Liaocheng,Shandong Province,252000 China)
出处
《中外医疗》
2022年第10期40-44,共5页
China & Foreign Medical Treatment
关键词
康复治疗
重症脑损伤
运动疗法
意识障碍
Rehabilitation treatment
Severe brain injury
Exercise therapy
Disturbance of consciousness
