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重症肺炎并呼吸衰竭以序贯机械通气开展临床治疗的效果分析 被引量:3

Analysis of the Effect of Clinical Treatment of Severe Pneumonia and Respiratory Failure with Sequential Mechanical Ventilation
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摘要 目的分析重症肺炎患者同时并发呼吸衰竭后,以序贯机械通气开展治疗的临床效果。方法随机选取2019年1月-2021年1月于该院接受相关治疗的重症肺炎并呼吸衰竭患者120例为研究对象,以随机抽取法进行对等分组,A组(n=60)以常规有创通气开展治疗,B组(n=60)以序贯机械通气法开展治疗,对比两组治疗结果。结果治疗后,B组有创通气时间(4.89±0.67)d、肺炎症状消失时间(8.25±1.34)d、总通气时间(6.06±1.37)d以及ICU住院时间(14.33±2.21)d较A组的(7.17±1.05)、(11.33±1.91)、(8.37±2.48)以及(18.67±3.06)d均明显更短,差异有统计学意义(t=14.179、10.225、6.315、8.906,P<0.05);B组的PaO_(2)(81.77±7.64)mmHg较A组的(72.31±8.29)mmHg明显更高,而PaCO_(2)(33.65±8.17)mmHg则低于A组的(62.46±9.03)mmHg,差异有统计学意义(t=6.499、18.325,P<0.05);且B组FEV1(2.64±0.35)L、FEVl%(72.35±9.11)%以及FEV1/FVC(64.69±8.89)%指标水平相较于A组的(1.93±0.31)L、(68.22±9.01)%、(58.56±8.72)%均明显更高,差异有统计学意义(t=11.762、2.496、3.813,P<0.05)。结论重症肺炎合并呼吸衰竭患者采用序贯机械通气法开展治疗可更快改善其临床症状,促进其氧合功能与肺功能恢复,值得推广。 Objective To analyze the clinical effects of sequential mechanical ventilation in patients with severe pneumonia and concurrent respiratory failure.Methods 120 patients with severe pneumonia and respiratory failure who received relevant treatment in the hospital from January 2019 to January 2021 were randomly selected as the research object.They were randomly divided into two groups.Group A(n=60)was treated with conventional mechanical ventilation and group B(n=60)was treated with sequential mechanical ventilation.The treatment results of the two groups were compared.Results After treatment,the days of invasive ventilation(4.89±0.67)d,days of disappearance of pneumonia(8.25±1.34)d,total ventilation days(6.06±1.37)d and ICU stay days(14.33±2.21)d in group B were significantly shorter than those(7.17±1.05)d,(11.33±1.91)d,(8.37±2.48)d and(18.67±3.06)d in group A,and the difference was statistically significant(t=14.179,10.225,6.315,8.906,P<0.05).The PaO_(2) of group B(81.77±7.64)mmHg was significantly higher than that of group A(72.31±8.29)mmHg.PaCO_(2)(33.65±8.17)mmHg was lower than that of group A(62.46±9.03)mmHg,and the difference was statistically significant(t=6.499,18.325,P<0.05).The levels of FEV1(2.64±0.35)L,FEVl%(72.35±9.11)%and FEV1/FVC(64.69±8.89)%in group B were significantly higher than those in group A(1.93±0.31)L,(68.22±9.01)%,(58.56±8.72)%,and the difference was statistically significant(t=11.762,2.496,3.813,P<0.05).Conclusion Patients with severe pneumonia combined with respiratory failure can be treated with sequential mechanical ventilation to improve their clinical symptoms more quickly and promote the recovery of oxygenation and lung function,which is worthy of promotion.
作者 石文 SHI Wen(Department of General Internal Medicine,Gannan People's Hospital,Gannan,Gansu Province,747000 China)
出处 《中外医疗》 2022年第5期41-44,共4页 China & Foreign Medical Treatment
关键词 重症肺炎 呼吸衰竭 序贯治疗 血气水平 机械通气 呼吸功能 Severe pneumonia Respiratory failure Sequential therapy Blood gas level Mechanical ventilation Respiratory function
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