摘要
骨质疏松症是病毒性肝炎肝硬化的并发症之一,有大量研究阐述了肝硬化患者中骨质疏松症的发病机制及治疗方法,而未进展至肝硬化阶段的慢性病毒性肝炎是否同样存在并发骨质疏松症的风险则尚无定论,多数研究就两者的关系给出了肯定的答复,但其发病机制和治疗等仍无系统的论断.本文回顾了近年来有关慢性病毒性肝炎及骨质疏松症的相关文献,就非肝硬化期慢性病毒性肝炎继发骨质疏松症的发生风险、可能的致病机制及治疗方案进行了系统的综述,以期明确两者的关系,提高临床医生关于本病的认识,并为临床诊治提供参考.
Osteoporosis is one of the complications of chronic viral hepatitis related cirrhosis,and the pathogenesis and treatment methods for osteoporosis have been extensively studied.However,whether chronic viral hepatitis is the risk factor for osteoporosis is still controversial.Some studies have demonstrated the relationship between them,but there is still no systematic judgment on its pathogenesis and treatment.In this review,we systematically summarize the risk,possible pathogenesis,and treatment scheme of osteoporosis secondary to non-cirrhosis chronic viral hepatitis,with an aim to clarify the relationship between chronic viral hepatitis and osteoporosis,remind clinicians to be alert to the possibility of osteoporosis complicated by chronic viral hepatitis,and provide support for clinical diagnosis and treatment.
作者
王平
高学松
张耀南
段雪飞
Ping Wang;Xue-Song Gao;Yao-Nan Zhang;Xue-Fei Duan(Department of General Medicine,Beijing Ditan Hospital,Capital Medical University,Beijing 100015,China;Orthopedic Department of Beijing Hospital,National Center of Gerontology,Institute of Geriatric Medicine,Chinese Academy of Medical Sciences,Beijing 100730,China)
出处
《世界华人消化杂志》
CAS
2022年第11期491-497,共7页
World Chinese Journal of Digestology
基金
国家十三五传染病防治科技重大专项,No.2018ZX10715-005.
