摘要
目的 观察心衰1号方治疗同时合并高血压病、糖尿病、冠心病并发慢性心力衰竭气虚血瘀证的临床疗效。方法 选取2018年5月—2021年5月北京市丰台中西医结合医院心内科收治的同时合并高血压病、糖尿病、冠心病并发慢性心力衰竭住院病人218例,采取数字表随机法分为对照组、治疗组,各109例,对照组采用常规西药治疗,治疗组在常规西药基础上加用心衰1号方治疗,比较临床疗效及左室射血分数(LVEF)、脑钠肽(BNP)。结果 治疗组总有效率为96.19%,高于对照组的75.73%,差异有统计学意义(P<0.05);两组治疗前LVEF、BNP水平比较差异均无统计学意义(P>0.05),治疗组治疗后LVEF高于对照组(P<0.05),BNP水平低于对照组(P<0.05)。结论 心衰1号方治疗同时合并高血压病、糖尿病、冠心病并发慢性心力衰竭气虚血瘀证的病人,可以提高临床总有效率,提高LVEF,降低BNP水平。
Objective To explore the clinical effects of Heart Failure No.1 Prescription in the treatment of patients with hypertension,diabetes,and coronary heart disease complicated with chronic heart failure(Qi deficiency and blood stasis syndrome).Methods A total of 218 patients concomitant with hypertension,diabetes,and coronary heart disease complicated with chronic heart failure were recruited and divided into control group and treatment group using random number table method,with 109 cases in each group.The patients in control group were treated with conventional western medicine,and the patients in treatment group were treated with conventional western medicine and Heart Failure No.1 Prescription.The clinical efficacy,left ventricular ejection fraction(LVEF),and brain natriuretic peptide(BNP)in two groups were compared.Results The total effective rate of treatment group was better than that of control group(96.19%and 75.73%,P<0.05).There were no significant differences in LVEF and BNP between two groups before treatment(P>0.05).After treatment,LVEF in treatment group was higher than that in control group(P<0.05),while BNP was lower than that in control group(P<0.05).Conclusion The combination of convention western medicine and Heart Failure No.1 Prescription for patients concomitant with hypertension,diabetes,and coronary heart disease complicated with chronic heart failure(Qi deficiency and blood stasis syndrome)can improve the clinical effective rate and LVEF,and reduce BNP level.
作者
刘玲玲
徐浩
李艳
李伟
张颖
王斐
戴晓玲
徐谦
冯浩新
LIU Lingling;XU Hao;LI Yan;LI Wei;ZHANG Ying;WANG Fei;DAI Xiaoling;XU Qian;FENG Haoxin(Beijing Fengtai Hospital of Integrated Traditional and Western Medicine,Beijing 100071,China;Xiyuan Hospital,China Academy of Chinese Medical Sciences,Beijing 100091,China)
出处
《中西医结合心脑血管病杂志》
2022年第9期1558-1561,共4页
Chinese Journal of Integrative Medicine on Cardio-Cerebrovascular Disease
关键词
高血压病
糖尿病
冠心病
慢性心力衰竭
气虚血瘀证
心衰1号方
左室射血分数
脑钠肽
hypertension
diabetes
coronary heart disease
chronic heart failure
Qi deficiency and blood stasis syndrome
Heart Failure No.1 Prescription
left ventricular ejection fraction
brain natriuretic peptide
