摘要
通过对实验动物使用情况和动物实验伦理不规范现状进行概述,指出替代动物发展的必要性及其伦理审查优势。总结和归纳替代动物实验的研究范围和伦理规范指导原则以及伦理规范审查的相关内容,讨论替代动物相关技术发展在科学研究和教学中的重要地位。列举替代动物研究伦理规范实施后追踪的相关情况,并对未来国内替代动物研究伦理评估标准的规范化重点发展方向作了展望。
This review provided an overview of the use of laboratory animals and the current status of ethical irregularities in animal experiments.The need for alternative animal development and its ethical review advantages were pointed out.We summarized the research scope and ethical guidelines for alternative animal experiments,as well as the relevant content of its ethical review.The importance of the development of alternative animal-related technologies in scientific research and experimental teaching was also discussed.The relevant situation of the follow-up after the implementation of the ethical standards for alternative animal research was listed and an outlook on the development direction of the standardization of the ethical evaluation was made for alternative animal research in the future.
作者
魏欣
徐维平
WEI Xin;XU Weiping(Institute of Intelligent Machines,Hefei Institute of Physical Science,Chinese Academy of Sciences,Hefei 230031,China;Science Island Branch,Graduate School of USTC,Hefei 230026,China;The First Affiliated Hospital of University of Science and Technology of China,Anhui Provincial Hospital,Hefei 230001,China)
出处
《生物学杂志》
CAS
CSCD
北大核心
2022年第3期1-5,共5页
Journal of Biology
基金
国家自然科学基金面上项目(52072360)。
关键词
替代动物
伦理
动物实验
体外模拟
3R原则
alternative animals
ethics
animal experiment
in vitro simulation
3R principle
