摘要
目的分析甲状腺结节发生的影响因素,以为临床预防措施的选择提供参考。方法回顾性收集2018年3月至2021年2月我院收治的58例甲状腺结节患者的临床资料,将其设为甲状腺结节组,收集同期我院57例健康体检者的体检资料,将其设为健康对照组。统计两组年龄、性别、婚姻情况、工作性质、吸烟史、饮酒史、经常熬夜、曾患有甲状腺疾病情况,检测总三碘甲状腺原氨酸(TT3)、总甲状腺素(TT4)、游离三碘甲状腺原氨酸(FT_(3))、游离甲状腺素(FT4)、促甲状腺激素(TSH)水平及抗甲状腺微粒体抗体(TMAb)和甲状腺球蛋白抗体(TGAb)。采用单因素及多因素Logistic回归分析甲状腺结节发生的影响因素。结果单因素分析结果显示,两组的年龄、性别及TT3、TT4、FT_(3)、TSH水平、TMAb、TGAb比较,差异具有统计学意义(P<0.05);两组的婚姻情况、工作性质、吸烟史、饮酒史、经常熬夜例数、曾患有甲状腺疾病例数及FT4水平比较,差异无统计学意义(P>0.05)。多因素Logistic回归分析结果显示,年龄、性别、TSH、TMAb是影响甲状腺结节发生的独立危险因素(P<0.05)。结论年龄、性别、TSH、TMAb是影响甲状腺结节发生的独立危险因素,临床上可针对以上因素进行干预,以降低患者甲状腺结节的发生风险。
Objective To analyze the influencing factors for the occurrence of thyroid nodules,so as to provide reference for the selection of clinical preventive measures.Methods The clinical data of 58 patients with thyroid nodules treated in our hospital from March 2018 to February 2021 were retrospectively collected and the patients were set as thyroid nodules group,and the physical examination data of 57 healthy people in our hospital at the same period were collected and the people were set as healthy control group.The age,gender,marital status,nature of work,smoking history,drinking history,often staying up late and having thyroid diseases were counted.The total triiodothyronine(TT3),total thyroxine(TT4),free triiodothyronine(FT_(3)),free thyroxine(FT4),thyroid stimulating hormone(TSH)levels,anti-thyroid microsomal antibody(TMAb)and thyroglobulin antibody(TGAb)were detected.Univariate and multivariate Logistic regression were used to analyze the influencing factors for the occurrence of thyroid nodules.Results Univariate analysis results showed that there were significant differences in age,gender,TT3,TT4,FT_(3),TSH levels,TMAb and TGAb between the two groups(P<0.05);there were no significant differences in marital status,nature of work,smoking history,drinking history,often staying up late cases,having thyroid diseases cases and FT4 level between the two groups(P>0.05).Multivariate Logistic regression analysis results showed that age,gender,TSH and TMAb were independent risk factors for the occurrence of thyroid nodules(P<0.05).Conclusion The age,gender,TSH and TMAb are independent risk factors for the occurrence of thyroid nodules.Clinical intervention can be carried out according to the above factors to reduce the risk of the occurrence of thyroid nodules.
作者
李刚
张晨阳
LI Gang;ZHANG Chenyang(Surgery Department,Tangyin County Hospital of Integrated Traditional Chinese and Western Medicine,Anyang 456150;No.2 General Surgery Department,Anyang People's Hospital,Anyang 455000,China)
出处
《临床医学研究与实践》
2022年第18期5-7,共3页
Clinical Research and Practice
