摘要
目的探讨百合固金汤加减在肺肾阴虚型慢性支气管炎患者中的效果.方法选取2020年6月-2021年6月天津市滨海新区大港医院收治的80例肺肾阴虚型慢性支气管炎患者,按随机数字表法分为两组,各40例.对照组给予常规西医治疗,观察组联用百合固金汤加减治疗,连续用药4周.比较两组临床疗效、中医证候积分、炎性因子水平、不良反应.结果观察组治疗总有效率高于对照组,有统计学差异(P<0.05);治疗前,两组咳嗽、咳痰、口干咽燥、燥热盗汗等中医证候积分与白介素-6(IL-6)、肿瘤坏死因子-α(TNF-α)、C反应蛋白(CRP)、白介素-8(IL-8)水平相比,无统计学差异(P>0.05);治疗后,观察组咳嗽、咳痰、口干咽燥、燥热盗汗等中医证候积分与IL-6、TNF-α、CRP、IL-8水平均低于对照组,有统计学差异(P<0.05);两组不良反应发生率相当,无统计学差异(P>0.05).结论百合固金汤加减能够有效减轻肺肾阴虚型慢性支气管炎患者各项临床症状,显著控制其机体的炎性反应,且无严重不良反应,安全可靠.
Objective To investigate the ffect of lily gold decoction in patients with chronic bronchitis.Methods 60 patients with lung renal Yin deficiency chronic bronchitis from June 2020 to June 2021 were divided into two groups and 40 each according to random numbers.The control group was given conventional westem medicine treatment,and the observation group was treated with lily solid gold soup in addition and subtraction for 4 consecutive weeks.The clinical fficacy,TCM syndrome integral,inflammatory factor level,and adverse reactions were compared between the two groups.Results The observation group was always more fficient than in the control groupstatistical dfence(Po0.05)pretherapy.he TCM syndome credits of cough.sputum,dry mouth and thoat,and hot night sweats were compared with interleukin-6(IL-6),umor necrosis factor-(TINF-α),C reactive protein(CRP),and interleukin-8(L-8)levels,no stistical difference(P>0.05)post-treatment,in the observation group,the IL-6.cough,sputum,TNF-α,CRP,and IL-8 levels were all lower than those in the control group,statistical diference(P<0.05);the incidence of adverse efects was comparable in the two groups,no statistical difference(P>0.05).Conclusion Add and decrease can efectively reduce the clinical symptoms of patients with lung kidney Yin defieieney chronie bronchitis,significantly control their inflammatory reaction,have no serious adverse reactions,and be safe and reliable.
作者
李岩
郭洋
Li Yan;Guo Yang(Respi ratory Department,Dagang Hospital,Binhai New Area,Tianjin 300270;Department of Traditional Chinese Medicine,Tianjin Huaxing Hospital,Tianjin 300270)
出处
《首都食品与医药》
2022年第11期121-123,共3页
Capital Food Medicine
关键词
慢性支气管炎
肺肾阴虚型
百合固金汤
炎性因子
不良反应
ehronic bronchitisluing and kidney Yin deficiency type
lily solid gold soup:inlammatory factors
adverse reactions
