摘要
目的探讨早期离子水平与血糖水平对急性百草枯中毒(Acute paraquat poisoning,APP)患者预后价值。方法收集2018年1月-2020年1月于本院就诊收治的62例APP患者的病例资料,2周内根据患者生存情况分为存活组(33例)与死亡组(29例),分别收集患者入院前、入院后第1、3天血糖平均血糖、血钙、血钠、血钾进行检测,探讨早期离子水平与血糖水平与APP患者预后的关系。结果存活组服毒量少于死亡组,各时间段血糖水平低于死亡组,各时间段血钾水平高于死亡组(P<0.05);采用Spearman相关分析结果显示APP患者入院前、入院第1 d、3 d血钾水平与病死呈负相关性(r=-0.654、-0.253、-0.432,P<0.05),APP患者入院前、入院第1 d、3 d血糖水平与病死呈正相关性(r=0.324、0.476、0.501,P<0.05);第1 d血钾水平判断患者预后的ROC曲线下面积最大,特异性及灵敏性最高,分别为0.796、79.98%、79.72%;第3 d血糖水平判断患者预后的ROC曲线下面积最大,特异性及灵敏性最高,分别为0.869、79.64%、82.66%。结论早期检测血钾、血糖水平对APP患者预后具有较好的预测能力。
Objective To investigate the prognostic value of early ion level and blood glucose level in patients with acute paraquat poisoning(Acute paraquat poisoning,APP).Methods 62 patients with app who were treated in our hospital from January 2018 to January 2020 were collected.Within 2 weeks,they were divided into survival group(33 cases)and death group(29 cases).The mean blood glucose,serum calcium,serum sodium and serum potassium were collected before admission,and on the 1st and 3rd days after admission,respectively,and the relationship between the early ion level and blood glucose level and the prognosis of APP patients was discussed.Results The drug consumption in the survival group was less than that in the death group,the blood glucose level in each time period was lower than that in the death group,and the serum potassium level in each time period was higher than that in the death group(P<0.05).The 3-day serum potassium level was negatively correlated with mortality(r=-0.654,-0.253,-0.432,P<0.05),and the blood glucose levels before admission,on the 1st and 3rd day of admission in APP patients were positively correlated with mortality(r=0.324,0.476,0.501,P<0.05);the area under the ROC curve of the blood potassium level on the 1st day was the largest,and the specificity and sensitivity were the highest,which were 0.796,79.98%,and 79.72%,respectively;the ROC curve of the blood sugar level on the 3rd day to judge the prognosis of the patient The lower area was the largest,with the highest specificity and sensitivity,which were 0.869,79.64%,and 82.66%,respectively.Conclusion The early level of blood potassium and blood glucose have a good predictive ability for the prognosis of APP patients.
作者
蔡晓辉
CAI Xiaohui(The First Affiliated Hospital of Henan University of Science and Technology,luoyang,471000,Henan,China)
出处
《新疆医学》
2022年第2期204-206,共3页
Xinjiang Medical Journal
关键词
离子水平
血糖水平
急性百草枯中毒
预后
ion level
blood glucose level
acute paraquat poisoning
prognosis
