摘要
近年来,心血管疾病发生率和死亡率显著上升,动脉粥样硬化(atherosclerosis,As)作为心血管疾病特别是冠状动脉疾病的主要病因,其预防和治疗迫在眉睫。Salusin-α是一种内源性的血管活性多肽,具有预防As的作用,但其对As的潜在影响和作用机制尚未完全阐明,有待进一步研究探讨。本文就Salusin-α在心血管疾病领域的研究进展作一综述。
In recent years,both the cardiovascular diseases incidence and mortality have increased significantly.The prevention and treatment of atherosclerosis is imminent,because the atherosclerosis is the main cause of cardiovascular diseases,especially coronary artery diseases.Salusin-αis an endogenous vasoactive polypeptide,which has the effect of preventing atherosclerosis,but neither its potential effect on atherosclerosis nor mechanism of action have been fully elucidated,hence it is still necessary to explore.This review discusses the research progress of Salusin-αin the field of cardiovascular diseases.
作者
陈明鑫
王宗保
王姝之
CHEN Mingxin;WANG Zongbao;WANG Shuzhi(Institute of Pharmacy and Pharmacology,School of Pharmaceutical Science,Hunan Collaborative Innovation Center of Molecular Target New Drug Research,University of South China,Hengyang 421001,China)
出处
《生命的化学》
CAS
2022年第2期326-331,共6页
Chemistry of Life
基金
湖南省自然科学基金项目(2019JJ40252,2020JJ5503)
湖南省教育厅科学研究项目(20K106)。
