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根治性膀胱切除术后发生尿路感染的危险因素 被引量:6

Risk factors of urinary tract infection after radical cystectomy
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摘要 目的探讨根治性膀胱切除术后尿路感染的危险因素。方法回顾性分析自2016年1月-2020年12月在新疆医科大学第一附属医院行根治性膀胱全切术并资料完整的164例患者临床病例信息。根据患者行根治性膀胱全切术后是否出现尿路感染将患者分为感染组和非感染组,应用χ^(2)检验和logistic回归分析发生尿路感染的危险因素。结果164例患者中男性144例、女性20例,术后尿路感染阳性组有39例,尿路感染阴性组有125例。单因素分析患者的尿流改道方式(P=0.003)、高血压(P=0.035)、术中输血(P=0.014)、术后肾积水(P<0.001)、术前白蛋白水平低(P=0.045)、术前肾积水(P=0.042)为尿路感染的危险因素。多因素分析患者高血压、术前肾积水和术后肾积水是尿路感染的独立危险因素(P<0.05),输血是其保护因素(P<0.05)。结论尿路感染是根治性膀胱切除术术后常见的并发症。高血压、术前肾积水和术后肾积水患者可能会增加术后尿路感染的风险。 Objective To investigate the risk factors of urinary tract infection after radical cystectomy.Methods Clinical data of 164 patients who underwent radical cystectomy during Jan.2016 and Dec.2020 at our hospital were retrospectively analyzed.Patients were divided into infection group and non-infection group according to whether they developed urinary tract infection after surgery.The risk factors were analyzed usingχ^(2) test and logistic regression.Results Among the 164 patients,144 were male and 20 were female,with 39 in the infection group and 125 in the non-infection group.Univariate analysis showed urinary diversion(P=0.003),hypertension(P=0.035),intraoperative blood transfusion(P=0.014),postoperative hydronephrosis(P<0.001),preoperative albumin grouping(P=0.045),and preoperative hydronephrosis(P=0.042)were risk factors of urinary tract infection.Multivariate analysis showed hypertension,preoperative hydronephrosis and postoperative hydronephrosis were independent risk factors of urinary tract infection(P<0.05),while blood transfusion was a protective factor(P<0.05).Conclusion Urinary tract infection is a common complication after radical cystectomy.Patients with hypertension,preoperative hydronephrosis and postoperative hydronephrosis may be at increased risk of postoperative urinary tract infection.
作者 艾米如拉江·艾尔肯 刘强 朱德康 刘坤 努尔艾力·提来克 张炜昕 王玉杰 Aimirulajiang AIERKEN;LIU Qiang;ZHU Dekang;LIU Kun;Nueraili TILAIKE;ZHANG Weixin;WANG Yujie(Department of Urology,First Affiliated Hospital of Xinjiang Medical University,Urumqi 830054,China)
出处 《现代泌尿外科杂志》 CAS 2022年第6期489-493,共5页 Journal of Modern Urology
关键词 膀胱肿瘤 根治性膀胱全切术 尿路感染 并发症 危险因素 bladder tumor radical cystectomy urinary tract infection complication risk factors
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