摘要
目的比较铥激光前列腺汽化剜除术(TmLEP)、经尿道前列腺等离子剜除术(PKEP)、经尿道前列腺电切术(TURP)治疗良性前列腺增生(BPH)的临床疗效。方法选取2018年6月至2019年6月本院收治的160例经手术治疗的BPH患者,根据手术方式不同分为TmLEP组55例、PKEP组53例、TURP组52例。比较3组围术期指标,术前和术后3个月的前列腺功能、最大尿流率、残余尿量和血清总前列腺特异抗原水平,记录术后3个月患者的生活质量。结果TmLEP组的手术时间、术中出血量、平均冲洗时间、切除组织质量以及术后3个月的前列腺症状评分(IPSS)、最大尿流率(Q_(max))、残余尿量(RUV)、血清总前列腺特异抗原(tPSA)、生活质量评分均优于PKEP组和TURP组,且PKEP组优于TURP组,组间比较差异均有统计学意义(F=11.859、56.526、25.463、11.566、9.080、20.378、14.186、58.490、19.000,均P<0.05);TmLEP组的术后并发症发生率低于TURP组,组间比较差异有统计学意义(χ^(2)=6.528,P<0.05);TmLEP组与PKEP组、PKEP组与TURP组术后并发症发生率分别比较,差异均无统计学意义(χ^(2)=1.497、2.057,均P>0.05)。结论与PKEP和TURP术比较,TmLEP术治疗BPH的效果更佳,值得应用。
Objective To compare the clinical efficacy of transurethral thulium laser enucleation of the prostate(Tm LEP),transurethral plasma kinetic enucleation of prostate(PKEP)and transurethral resection of prostate(TURP)in the treatment of benign prostatic hyperplasia(BPH).Methods One hundred and sixty patients with BPH who underwent surgical treatment in our hospital from June 2018 to June 2019 were selected and divided into Tm LEP group(n=55),PKEP group(n=53)and TURP group(n=52)according to the surgical methods.The perioperative indicators of the three groups were compared,prostate function,maximum urinary flow rate,residual urine volume and serum total prostate-specific antigen level before and 3months after surgery,and the quality of life of the patients at 3 months after surgery was recorded.Results In the Tm LEP group,operation time,intraoperative blood loss,mean flushing time,quality of resected tissue,and International Prostate Symptom Score(IPSS),the maximum urine flow rate(Qmax),residual urine volume(RUV),serum total prostate specific antigen(t PSA),and quality of life scores were better than those in the PKEP group and the TURP group,and the PKEP group was better than the TURP group.The differences between the groups were all statistically significant(F=11.859,56.526,25.463,11.566,9.080,20.378,14.186,58.490,19.000,all P<0.05);the incidence of postoperative complications in the Tm LEP group was lower than that in the TURP group,and the difference was statistically significant between groups(χ^(2)=6.528,P<0.05);there were all no statistically significant difference in the incidence of postoperative complications between Tm LEP group and PKEP group,between the PKEP group and the TURP group(χ^(2)=1.497,2.057,all P>0.05).Conclusion Compared with PKEP and TURP,TmLEP has more effective in the treatment of BPH and is worthy of application.
作者
高子剑
李健
GAO Zi-jian;LI Jian(Department of Urology Surgery,General Hospital of Northern Theater Command,Shenyang,Liaoning,110016,China)
出处
《中国冶金工业医学杂志》
2022年第3期258-260,共3页
Chinese Medical Journal of Metallurgical industry
