摘要
阿尔茨海默病是一种老年人最常见的痴呆症,是一个日益严重的全球健康问题。脑白质高信号是脑白质病变的影像学表现,近些年神经影像学研究发现脑白质高信号是认知障碍发生发展的重要危险因素。现就脑白质高信号的病因、发病机制及其与阿尔茨海默病病理、认知功能等方面内容进行阐述。
Alzheimer ’s disease is one of the most common dementias in the elderly,and it is a growing global health problem. White matter hyperintensity is an imaging manifestation of white matter lesions. In recent years,neuroimaging studies have found that white matter hyperintensity is an important risk factor for the development of cognitive impairment. This article first summarizes the etiology,pathogenesis and severity assessment of white matter hyperintensity,and then explains the relationship between white matter hyperintensity and Alzheimers’ disease pathology,cognitive function,and psychiatric symptoms.
作者
梁春华
肖小华
LIANG Chunhua;XIAO Xiaohua(The First Affiliated Hospital of Shenzhen University,Shenzhen 518035,China)
出处
《中国实用神经疾病杂志》
2022年第4期513-517,共5页
Chinese Journal of Practical Nervous Diseases
关键词
阿尔茨海默病
脑白质高信号
脑白质病变
认知障碍
精神症状
Alzheimers’ disease
White matter hyperintensity
White matter lesions
Cognitive impairment
Mental symptoms
