摘要
慢性乙型病毒性肝炎(CHB)是目前我国最常见的慢性肝病,也是导致肝硬化及肝癌的常见病因。近年来,非酒精性脂肪性肝病(NAFLD)发病率急剧升高,导致CHB合并NAFLD愈发常见。与单纯CHB或单纯NAFLD患者相比,CHB合并NAFLD患者发生肝纤维化、肝硬化,甚至肝癌的风险显著增加。乙型肝炎病毒与肝细胞脂肪变性共同作用于肝脏可加速肝纤维化进程,准确诊断CHB合并NAFLD患者肝纤维化及肝脂肪变性程度在病情监测、指导临床干预及改善患者预后方面均具有重要价值。目前,肝脏穿刺活检仍为诊断肝纤维化、肝脂肪变性的金标准,但因其有创性且并发症多等缺陷,在临床中难以推广应用,临床亟需一种非侵入性诊断技术,超声作为无创诊断技术近年来发展迅速,以其实时、可视化等优势在肝脏疾病诊断应用日益广泛。随着弹性成像与人工智能等新技术的发展,多种新技术与超声成像的融合不断加深,使超声能给出更加客观、快速的诊断。本文综合介绍了超声弹性成像技术、超声衰减成像技术、超声人工智能技术在CHB合并NAFLD诊断中的应用价值。
Chronic hepatitis B(CHB) is the most common chronic liver disease in China,as well as the common cause of cirrhosis and liver cancer.In recent years,the incidence of non-alcoholic fatty liver disease (NAFLD) has increased rapidly,resulting in more and more common CHB combined with NAFLD.Patients with CHB combined with NAFLD have a significantly increased risk of liver fibrosis,cirrhosis and even liver cancer compared with patients with CHB alone or NAFLD alone.The combined action of hepatitis B virus and hepatocellular steatosis on the liver can accelerate the progression of liver fibrosis.Accurate diagnosis of liver fibrosis and steatosis in patients with CHB complicated with NAFLD is of great value in disease monitoring,guiding clinical intervention and improving the prognosis of patients.At present,liver biopsy is still the gold standard in the diagnosis of liver fibrosis and liver steatosis,but because of its many defects such as invasive and complications,difficult to promote in the clinical application and clinical needs to be a non-invasive diagnostic technology,ultrasonography as a noninvasive diagnosis technology is developing rapidly in recent years,such as real-time,visual advantage is becoming more and more widely applied in liver disease diagnosis.With the development of new technologies such as elastography and artificial intelligence,the integration of multiple new technologies and ultrasound imaging is deepening,enabling ultrasound to provide more objective and rapid diagnosis.This paper introduces the application value of ultrasound elastography,ultrasonic attenuation imaging and ultrasonic artificial intelligence in the diagnosis of chronic hepatitis B complicated with NAFLD.
作者
黄秀玲
冯程
董常峰
Huang Xiuling;Feng Cheng;Dong Changfeng(The First Clinical Medical College of Guangdong Medical University,Guangdong Zhanjiang 524000,China;Department of Ultrasound,Guangdong Medical University,Shenzhen Third People's Hospital,Guangdong Shenzhen 518112,China)
出处
《新发传染病电子杂志》
2022年第2期95-98,共4页
Electronic Journal of Emerging Infectious Diseases
基金
国家自然科学基金重点项目(61031003)
深圳市第三人民医院临床类研究项目(G2022018)。
关键词
超声弹性成像
超声衰减成像
入工智能
慢性乙型病毒性肝炎
非酒精性脂肪性肝病
Ultrasonic elastography
Ultrasonic attenuation imaging
Artificial intelligence
Chronic viral hepatitis B
Non-alcoholic fatty liver disease
