摘要
急性冠状动脉综合征(ACS)是危害人类健康的最严重心血管疾病之一。长期以来,动脉粥样硬化斑块破裂(PR)导致的斑块内容物释放伴随附壁血栓形成被认为是ACS形成的主要机制。随着光学相干断层成像(OCT)的应用,人们认识到除了PR,斑块侵蚀(PE)是ACS的另外一种重要而且常见的病理学机制。近年来对于PE的研究已经取得了一定进展,文章将对PE的诊断以及治疗的研究进展做一综述。
Acute coronary syndrome(ACS)is one of the most serious cardiovascular diseases endangering human health.For a long time,plaque rupture(PR),the release of plaque contents accompanying and the formation of mural thrombus are considered as the major mechanism for the formation of ACS.With the application of optical coherence tomography(OCT),it is realized that,in addition to PR,plaque erosion(PE)is another important and common pathological mechanism of ACS.In recent years,the research on PE has made good progress.This paper will summarize the research progress on the diagnosis and treatment of PE.
作者
朱心忻
乔虹
ZHU Xinxin;QIAO Hong(Department of Endocrinology,the Second Affiliated Hospital of Harbin Medical University,Harbin,Heilongjiang 150001,China)
出处
《中国动脉硬化杂志》
CAS
2022年第7期628-632,共5页
Chinese Journal of Arteriosclerosis
基金
国家自然科学基金项目(8187120246)。
关键词
斑块侵蚀
抗栓治疗
生物标志物
plaque erosion
antithrombotic therapy
biomarker
