摘要
近年来,血液系统肿瘤尤其白血病、淋巴瘤的发病率逐渐上升,且经过传统的化疗或放疗后不少患者出现原发病的复发、难治,临床治疗上极具挑战,因此拓展治疗领域、探索新的治疗药物非常有必要。目前不少研究显示天然中药在肿瘤的治疗方面有其独特优势,抗肿瘤谱广,本文就黄芩苷在血液肿瘤的作用机制和逆转耐药的功能及分子机制研究进展做一综述。
The incidence of hematological malignancies was increased in recent years.A lot of patients suffered from relapse after traditional chemotherapy or radiotherapy.It’s a great challenge to cure it.Hence it is necessary to find new treatment methods and drugs.Recently,some studies found that natural traditional Chinese medicine had special advantages in treatment of tumor.In this review,discussed the molecular mechanism of baicalin in treatment of hematological malignancies reverse of drug resistance.
作者
段晓晖
李宏
王健红
吕垚
王世雄
王冰璇
梁蓉
DUAN Xiaohui;LI Hong;WANG Jianhong;LV Yao;WANG Shixiong;WANG Binxuan;LIANG Rong(The Second Clinical Medical College of Shaanxi University of Chinese Medicine,xi’an,shaanxi 712046,China;The First Affiliated Hospital of Air Force Military Medical University,Xi’an,shaanxi 710032,China)
出处
《转化医学杂志》
2022年第3期188-191,187,共5页
Translational Medicine Journal
基金
国家自然科学基金项目(81370641)
西京医院学科助推计划项目(XJZT_(1)8ML81)。
关键词
黄芩苷
血液肿瘤
逆转耐药
Baicalin
Hematological malignancies
Reverse resistance
