摘要
MRI对肝脏疾病的检出与诊断具备重要作用,肝胆特异性对比剂作为一种新型的细胞特异性对比剂,能被正常肝细胞特异性摄取,而功能受损的肝细胞摄取减少,这一特性使其不仅可以获得整体肝脏功能信息,在节段性肝功能的评估方面更加具有独特优势。本文首先介绍了肝胆特异性对比剂MRI的原理,并就其在肝脏弥漫性疾病如脂肪肝、肝纤维化、肝炎、肝硬化、肝缺血等方面的应用进展及其结合人工智能方法在肝功能评估的应用进行综述。
MRI plays an important role in the detection and diagnosis of liver disease.As a new type of cell-specific contrast agent,hepatobiliary-specific contrast agent can be specifically taken up by normal hepatocytes,while the uptake of impaired hepatocytes is reduced.This characteristic not only makes it possible to obtain information of the overall liver function,but also has unique advantages in the assessment of segmental liver function.This article first introduces the principle of hepatobiliary specific contrast agent MRI,and the application progress in liver diffuse disease such as fatty liver,liver fibrosis,hepatitis,cirrhosis,liver ischemia is reviewed.The combination of hepatobiliary specific contrast agent and artificial intelligence methods in liver function assessment have also been reviewed.
作者
任雪
刘爱连
赵莹
REN Xue;LIU Ailian;ZHAO Ying(Department of Radiology,the First Affiliated Hospital of Dalian Medical University,Dalian 116011,China;Engineering Research Center for Artificial Intelligence in Medical Imaging,Dalian 116011,China)
出处
《磁共振成像》
CAS
CSCD
北大核心
2022年第6期151-154,159,共5页
Chinese Journal of Magnetic Resonance Imaging
基金
国家自然科学基金面上项目(编号:61971091)
吴阶平医学基金会临床科研专项资助基金(编号:320.6750.2021-06-25)。
关键词
磁共振成像
肝脏
肝功能
肝脏弥漫性疾病
肝胆特异性对比剂
钆贝葡胺
钆塞酸二钠
人工智能
magnetic resonance imaging
liver
liver function
diffuse liver disease
hepatocyte-specific contrast media
gadobenate dimeglumine
gadolinium-ethoxybenzyl-diethylenetriamine
artificial intelligence
