摘要
目的了解河北省水源性高碘地区居民碘营养状况,为采取针对性防治措施和精准干预策略提供依据。方法根据《全国水源性高碘地区监测方案(2018版)》,在河北省的5个市35个县(市、区,以下简称县)进行水源性高碘监测。按照2017年河北省居民生活饮用水水碘调查结果,各监测县将水碘中位数>100μg/L的行政村按照水碘值进行排序,采用系统抽样法,每个县抽取5个行政村,如果少于5个行政村则全部抽取(如有水碘中位数>300μg/L的行政村,则至少抽取1个),在抽中行政村开展居民生活饮用水水碘,8~10岁儿童盐碘、尿碘、甲状腺容积,以及孕妇盐碘、尿碘检测。采用中国疾病预防控制中心国家碘缺乏病参照实验室推荐的"适合缺碘及高碘地区水碘检测的方法"检测水碘,半定量法检测盐碘,《尿中碘的砷铈催化分光光度测定方法》(WS/T 107-2006)检测尿碘,B超法检测儿童甲状腺容积。结果35个县共监测167个村,采集水样239份,水碘中位数为163.95μg/L,范围为5.53~930.82μg/L。共检测盐样6772份,检出未加碘盐3495份,未加碘盐率为51.61%(3495/6772)。共检测儿童尿样6101份,尿碘中位数为328.00μg/L。在35个县中对8~10岁儿童6103人进行甲状腺检查,检出甲状腺肿(甲肿)306人,甲肿率为5.01%(306/6103);检出甲状腺结节34人,甲状腺结节检出率为0.56%(34/6103)。共检测孕妇尿样713份,尿碘中位数为221.70μg/L。结论河北省水源性高碘地区儿童碘营养处于过量水平,孕妇碘营养处于适宜水平。除采取停供碘盐措施外,应进一步扩大高碘地区改水降碘工程覆盖面积,加强对重点人群的碘营养状况监测。
Objective To dynamically investigate the iodine nutritional status of residents in water source high iodine areas in Hebei Province,so as to provide basis for taking targeted prevention and control measures and accurate intervention strategies.Methods According to the"National Monitoring Program for Water Source High Iodine Areas(2018 Edition)",water source high iodine monitoring was carried out in 5 cities and 35 counties(cities,districts,hereinafter referred to as counties)of Hebei Province.According to the survey results of drinking water iodine of residents of Hebei Province in 2017,the administrative villages with a median water iodine above 100μg/L were sorted according to the water iodine value.The systematic sampling method was adopted.Five administrative villages were selected in each county,if there were less than 5 administrative villages,all of them were selected(if the median water iodine was>300μg/L,at least one village shall be selected).The iodine content in drinking water of residents among the monitoring sites,salt iodine,urinary iodine and thyroid volume of children aged 8-10,as well as salt iodine and urinary iodine of pregnant women were tested.Water iodine was detected by the"Method Suitable for the Detection of Water Iodine in Iodine Deficient and High Iodine Areas"recommended by the National Iodine Deficiency Reference Laboratory of the Chinese Center for Disease Control and Prevention.Salt iodine was detected by semi quantitative method.Urinary iodine was detected by"Arsenic Cerium Catalytic Spectrophotometry Method"(WS/T 107-2006).Children's thyroid volume was detected by B-ultrasound.Results A total of 239 water samples were collected in 167 villages,35 counties,the median water iodine was 163.95μg/L,ranging from 5.53-930.82μg/L.A total of 6772 edible salt samples were monitored,including 3495 non-iodine salt samples and the rate of non-iodine salt was 51.61%(3495/6772).A total of 6101 urine samples of children were tested,the median urinary iodine was 328.00μg/L.A total of 6103 children aged 8-10 were carried out B-ultrasound detection of thyroid volume in 35 counties.The goiter rate of children was 5.01%(306/6103),and the rate of nodules was 0.56%(34/6103).A total of 713 urine samples of pregnant women were tested,and the median urinary iodine was 221.70μg/L.Conclusions The iodine nutrition of children in water source high iodine areas of Hebei Province is at an excess level,and the iodine nutrition of pregnant women is at an appropriate level.In addition to stopping the supply of iodized salt,we should further expand the coverage of water improvement and iodine reduction projects in high iodine areas,and strengthen the monitoring of iodine nutrition status of key populations.
作者
尹志娟
贾丽辉
徐栋
李桐
田慎谦
杜永贵
马景
Yin Zhijuan;Jia Lihui;Xu Dong;Li Tong;Tian Shenqian;Du Yonggui;Ma Jing(Institution for Endemic Disease Prevention and Control,Hebei Provincial Center for Disease Control and Prevention,Shijiazhuang 050021,China)
出处
《中华地方病学杂志》
CAS
北大核心
2022年第6期455-459,共5页
Chinese Journal of Endemiology
基金
河北省卫生与计划生育委员会指导性课题(20200698)。
关键词
碘
饮用水
食用盐
尿
甲状腺肿
Iodine
Drinking water
Edible salt
Urine
Goiter
