摘要
目的:观察陇中损伤胶囊治疗骨质疏松性椎体压缩骨折(OVCF)经皮椎体后凸成形术(PKP)术后残留疼痛的临床效果。方法:将符合纳入标准的骨质疏松性椎体压缩骨折(OVCF)经皮椎体后凸成形术(PKP)术后患者90例,随机分为两组各45例。对照组行PKP手术,治疗组在对照组基础上予陇中损伤胶囊,疗程6个月。两组患者均予抗骨质疏松治疗。在治疗前后分别动态记录两组患者的视觉模拟疼痛评分(VAS评分)、Oswestry残损指数(ODI评分)和BMD值变化。结果:治疗组、对照组两组治疗总有效率分别为95.6%和82.2%,两组比较,差异有统计学意义(P﹤0.05);治疗后,两组患者VAS、ODI评分较治疗前均明显下降,治疗后4周VAS、ODI评分明显低于治疗后1周(P﹤0.05)。且治疗组在治疗1、4周末VAS、ODI评分均显著低于对照组(P﹤0.05)。治疗后,治疗组BMD值较对照组均明显升高(P﹤0.05)。结论:陇中损伤胶囊治疗骨质疏松性椎体压缩骨折PKP术后残留疼痛疗效较好、安全可靠,并一定程度可改善骨代谢。
Objective:To observe the clinical effect of Longzhong Sunshang apsule on residual pain after percutaneous kyphoplasty(PKP)for osteoporotic vertebral compressive fracture(OVCF).Methods:90 cases of PKPpostoperative patients with OVCF,who met the inclusion criteria,were randomly divided into two groups,45 cases in each group.The control group was treated by PKP,while the treatment group was treated with Longzhong Sunshang capsule on the basis of control group,for 6 months.The patients in both groups were given the treatment of anti osteoporosis.The changes of visual analogue scale(VAS score),Oswestry disability index(ODI score)and BMD value of patients were dynamically recorded respectively in two groups before and after treatment.Results:The total effective rate was 95.6%in treatment group and 82.2%in control group respectively;compared between two groups,the difference was statistically significant(P﹤0.05).After treatment,the scores of VAS and ODI of patients in two groups were significantly lower than those before treatment;and the scores of VAS and ODI after 4 weeks of treatment were significantly lower than those after 1 week of treatment(P﹤0.05).The scores of VAS and ODI of treatment group were significantly lower than those of control group after 1 and 4 weeks of treatment(P﹤0.05).After treatment,BMD value of treatment group was significantly higher than that of control group(P﹤0.05).Conclusion:The clinical effect of Longzhong Sunshang capsule on residual pain after percutaneous kyphoplasty(PKP)for osteoporotic vertebral compressive fracture(OVCF)is better,safe and reliable,which can improve bone metabolism to a certain extent.
作者
张超
王想福
赵道洲
张万乾
雒永生
刘贵平
陈伟国
桑廷瑞
杨焕莹
郑刚
ZHANG Chao;WANG Xiang-fu;ZHAO Dao-zhou(Gansu University of Traditional Chinese Medicine,Lanzhou 730000,China;不详)
出处
《山西中医》
2022年第7期18-20,共3页
Shanxi Journal of Traditional Chinese Medicine
基金
甘肃省自然科学基金(编号:20JR10RA357)
甘肃省兰州市指导性计划项目(编号:2019-ZD-116)。
关键词
骨质疏松性椎体骨折
经皮椎体后凸成形术
陇中损伤胶囊
中医药疗法
osteoporotic vertebral compressive fracture
percutaneous kyphoplasty
Longzhong Sunshang capsules
therapy of TCM
