摘要
心血管病严重影响人类健康.尽管溶栓、介入等冠状动脉再灌注治疗策略被广泛应用并取得成功,急性心肌梗死的发病率和死亡率仍然很高,依然是心力衰竭的最常见原因.现代生物医学围绕冠心病的病理生理与发病机制,包括动脉粥样硬化、血小板血栓形成和免疫炎症等,发现和揭示了冠心病发生发展的新靶点和新机制.中、西医在冠心病防治方面各有所长,可以优势互补,在宏观医理、辨证与治未病、扶正等方面,可以采用“中医为体、西医为用”;在微观病生理、分子机制、靶向治疗等方面,则可尝试“西医为体、中医为用”;最终以提高临床疗效为首要目标,科学诠释中医对冠心病的诊、防、治的内涵,提升冠心病早期诊断、通治与辨治、中西药并用等诊疗创新能力.
Cardiovascular disease is the leading cause of death worldwide.Although coronary artery reperfusion treatment strategies such as thrombolysis and intervention are widely use and successful,the morbidity and mortality of acute myocardial infarction are still high,and it is still the most common cause of heart failure.Biomedical studies focus on the pathophysiology and pathogenesis of coronary heart disease,including atherosclerosis,platelet thrombosis,and immune inflammation.It has identified and revealed new targets and new mechanisms for the onset and development of coronary heart disease.Traditional Chinese medicine and western medicine have their own strengths in the prevention and treatment of coronary heart disease,and can complement each other.In terms of macromedicine,syndrome differentiation and prevention of disease,and strengthening of the body,“Chinese medicine is the principle and western medicine as practice”.For the microscopic pathophysiology,molecular mechanism,and targeted therapy and other aspects,we can try“western medicine is the principle and Chinese medicine as practice”.Ultimately,improving clinical efficacy is the primary goal,interpreting the scientific connotation of the diagnosis,prevention and treatment of coronary heart disease by Chinese medicine,and improving diagnosis and treatment innovations such as early diagnosis,general treatment and differentiation treatment for coronary heart disease with the combined use of Chinese and western medicine.
作者
项耀祖
XIANG YaoZu(School of Life Sciences and Technology,Tongji University,Shanghai 200092,China)
出处
《中国科学：生命科学》
CSCD
北大核心
2022年第6期832-839,共8页
Scientia Sinica(Vitae)
基金
国家自然科学基金(批准号:81822048)
中央高校基本科研业务费专项资金(批准号:22120220162)资助。
关键词
冠心病
心肌梗死
中医药
现代医学
防治
coronary heart disease
myocardial infarction
traditional Chinese medicine
western medicine
prevention and treatment
