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胰岛素连续滴注在糖尿病合并髋部骨折患者围术期的应用效果 被引量:1

The Effect of Continuous Infusion of Insulin in the Perioperative Period of Diabetic Patients with Hip Fracture
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摘要 目的探究在糖尿病合并髋部骨折患者的围术期将胰岛素连续滴注法进行应用的临床效果。方法选取该院2019年2月—2021年10月在该院接受治疗的110例糖尿病合并髋部骨折患者为研究对象,对患者展开手术治疗,在围术期期间给予患者不同胰岛素干预方法,将患者分为两组,对照组(n=55)给予多次皮下胰岛素注射,研究组(n=55)给予胰岛素连续滴注,对不同胰岛素使用方法下患者的血糖指标变化、患者骨折恢复有效率和不良反应发生率进行比较。结果治疗前,两组患者的血糖水平均较高,差异无统计学意义(P>0.05),治疗后,患者血糖均得以降低,研究组血糖控制效果更好,空腹血糖值和餐后2 h血糖值分别为(6.20±2.33)mmol/L和(8.56±2.34)mmol/L,均低于对照组,差异有统计学意义(t=3.711、2.966,P<0.05)。研究组治疗总有效率为96.36%,显著高于对照组的81.82%,差异有统计学意义(χ^(2)=5.986,P<0.05)。研究组不良反应发生率为9.09%低于对照组的25.45%,,差异有统计学意义(χ^(2)=5.153,P<0.05)。结论在糖尿病合并髋部骨折患者围术期中给予患者胰岛素泵连续滴注法,可改善患者的血糖水平,将其维持在平衡状态,并促进患者的骨折恢复,减少患者不良反应发生率。 Objective To explore the clinical effect of continuous insulin infusion in the perioperative period of diabetic patients with hip fracture.Methods 110 patients with diabetes complicated with hip fracture who were treated in the hospital from February 2019 to October 2021 were selected as the research object to undergo surgical treatment.During the perioperative period,the patients were given different insulin intervention methods.The patients were divided into two groups.The control group(n=55)was given multiple subcutaneous insulin injections,and the study group(n=55)was given continuous insulin infusion.The changes of blood glucose indexes under different insulin use methods were analyzed The effective rate of fracture recovery and the incidence of adverse reactions were compared.Results Before treatment,the blood glucose of the two groups was higher on average,with no significant difference(P>0.05).After treatment,the blood glucose of the patients was reduced,and the blood glucose control effect of the study group was better.The fasting blood glucose and 2-hour postprandial blood glucose were(6.20±2.33)mmol/L and(8.56±2.34)mmol/L,respectively,lower than that of the control group,the difference was statistically significant(t=3.711,2.966,P<0.05).The total effective rate of treatment in the study group was 96.36%,which was significantly higher than 81.82%of the control group,the difference was statistically significant(χ^(2)=5.986,P<0.05).The incidence of adverse reactions in the study group was 9.09%lower than that in the control group(25.45%),the difference was statistically significant(χ^(2)=5.153,P<0.05).Conclusion The continuous infusion of insulin pump in the perioperative period of diabetic patients with hip fracture can improve the blood glucose level and maintain it in a balanced state.And promote the fracture recovery of patients,reduce the incidence of adverse reactions in patients.
作者 叶家炜 陈镁 YE Jiawei;CHEN Mei(No.900 Hospital of Joint Logistics Support Force,Fuzhou,Fujian Province,350001 China)
出处 《糖尿病新世界》 2022年第12期75-78,共4页 Diabetes New World Magazine
关键词 胰岛素连续滴注 糖尿病合并髋部骨折 围术期干预 临床效果 Continuous infusion of insulin Diabetes complicated with hip fracture Perioperative intervention Clinical effect
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