摘要
目的:分析超声引导下经皮微波消融治疗原发性肝癌患者术后出血的危险因素。方法:选取2018年8月-2021年9月本院收治行超声引导下经皮微波消融治疗原发性肝癌患者183例为研究对象。记录超声引导下经皮微波消融治疗原发性肝癌患者临床疗效及出血情况,分析超声引导下经皮微波消融治疗原发性肝癌患者术后出血的危险因素。结果:183例超声引导下经皮微波消融术后共有9例出血,出血率为4.91%。性别、年龄、肿瘤直径不是影响超声引导下经皮微波消融治疗原发性肝癌患者术后出血的单因素(P>0.05)。合并肝硬变、凝血酶原时间延长、Child-PughB/C级、血小板数量减少及再次行微波消融术的原发性肝癌患者术后出血率更高(P<0.05)。经多元Logistic回归分析可知,肝硬变、凝血酶原时间、Child-Pugh分级及血小板数量是术后出血的独立危险因素(P<0.05)。微波消融次数不是术后出血的因素(P>0.05)。结论:超声引导下经皮微波消融治疗原发性肝癌患者术后出血的危险因素为凝血功能障碍、合并肝硬变、血小板减少及Child-PughB/C级;对于出血高危素患者,需慎重行微波消融术。
Objective:To analyze the risk factors of postoperative hemorrhage in patients with primary liver cancer treated by ultrasound-guided percutaneous microwave ablation.Methods:From August 2018 to September 2021,183 patients with primary liver cancer treated by ultrasour-guided percutaneous microwave ablation were selected as the research subjects.The clinical efficacy and bleeding of patients with primary liver cancer treated by ultrasound-guided percutaneous microwave ablation were recorded,and the risk factors of postoperative bleeding in patients with primary liver cancer treated by ultrasound-guided percutaneous microwave ablation were analyzed.Results:There were 9 cases of bleeding after 183 cases of ultrasound-guided percutaneous microwave ablation,the bleeding rate was 4.91%.Gender,age and tumor diameter were not single factors influencing postoperative hemorrhage in patients with primary liver cancer treated by ultrasound-guided percutaneous microwave ablation(P>0.05).The postoperative bleeding rate of HCC patients complicated with cirrhosis,prothrombin time,child-pughb/C grade,reduced platelet count and microwave ablation was higher(P<0.05).Multiple Logistic regression analysis showed that cirrhosis,prothrombin time,child-pugh grade and platelet count were independent risk factors for postoperative bleeding(P<0.05).The frequency of microwave ablation was not a factor of postoperative bleeding(P>0.05).Conclusions:The risk factors of postoperative hemorrhage in patients with primary liver cancer treated by ultrasound-guided percutaneous microwave ablation are coagulation dysfunction,cirrhosis,thrombocytopenia and Child-pughb/C grade.For bleeding patients with high risk factors,microwave ablation should be carefully performed.
作者
李鑫
Li Xin(Department of Interventional Surgery,Deyang People's Hospital,Deyang 618099,Sichuan,China)
出处
《四川生理科学杂志》
2022年第6期1000-1002,1017,共4页
Sichuan Journal of Physiological Sciences
关键词
超声引导下经皮微波消融
原发性肝癌
术后出血
危险因素
Ultrasound-guided percutaneous microwave ablation
Primary liver cancer
Postoperative bleeding
Risk factors for
