摘要
神经内分泌肿瘤(neuroendocrine neoplasm,NEN)是一类起源于肽能神经元和神经内分泌细胞,具有神经内分泌分化并表达神经内分泌标志物的少见肿瘤,可发生于全身各处,以肺及胃肠胰NEN(gastroenteropancreatic neuroendocrine neoplasm,GEP-NEN)最常见。国内外研究数据均提示,NEN的发病率在不断上升。美国流行病学调查结果显示,与其他类型肿瘤相比,NEN的发病率上升趋势更为显著。中国抗癌协会神经内分泌肿瘤专委会在现有循证医学证据基础上,结合已有国内外指南和共识,制订了首版中国抗癌协会神经内分泌肿瘤诊治指南,为临床工作者提供参考。
Neuroendocrine neoplasm(NEN)is a kind of rare tumor that originated from peptidergic neurons and neuroendocrine cells,which has neuroendocrine differentiation and expresses neuroendocrine markers.NEN occurs in all parts of the body,especially in lung,stomach,intestine and pancreas.Domestic and international research data suggested that the incidences of NEN were rising.The results of epidemiological investigation showed that compared with other types of tumors,the incidences of NEN increased more significantly.On the basis of existing evidence,combined with domestic and international guidelines and consensus,the Society of Neuroendocrine Neoplasm of China Anti-Cancer Association has formulated its first guideline for diagnosis and treatment of NEN as reference for clinical physicians.
作者
中国抗癌协会神经内分泌肿瘤专业委员会
陈洁
聂勇战
吴文铭
Society of Neuroendocrine Neoplasm of China Anti-Cancer Association;CHEN Jie;NIE Yongzhan;WU Wenming
出处
《中国癌症杂志》
CAS
CSCD
北大核心
2022年第6期545-580,共36页
China Oncology
关键词
神经内分泌肿瘤
诊断
治疗
指南
Neuroendocrine neoplasm
Diagnosis
Treatment
Guideline
