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戈舍瑞林联合妇科千金胶囊对子宫内膜异位症术后血流动力学及雌激素水平的影响 被引量:16

Effect of goserelin combined with Fukeqianjin capsule on hemodynamics and estrogen level in patients with endometriosis
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摘要 目的 分析戈舍瑞林联合妇科千金胶囊对子宫内膜异位症术后血流动力学及雌激素水平的影响。方法 150例子宫内膜异位症患者随机均分为对照组(戈舍瑞林治疗)和联合组(戈舍瑞林联合妇科千金胶囊治疗)。比较治疗前后两组患者血流动力学及雌激素水平的变化。结果 联合组治疗总有效率高于对照组(P<0.05)。与治疗前比较,治疗后两组中医症候积分、子宫动脉左侧和右侧阻力指数、搏动指数、血清黄体生成素、促卵泡激素、雌二醇水平均降低,子宫动脉最大血流速度升高(P<0.05);且联合组较对照组改善更为明显(P<0.05)。结论 戈舍瑞林联合妇科千金胶囊治疗子宫内膜异位症术后患者安全有效,且改善其血流动力学及雌激素水平。 Aim To analyze the effect of goserelin combined with Fukeqianjin capsule on postoperative hemody-namics and estrogen level in patients with endometriosis.Methods 150 patients with endometriosis were randomly di-vided into the control group(goserelin)and the combined group(goserelin combined with Fukeqianjin capsule).The changes of hemodynamics and estrogen levels were compared between the two groups before and after treatment.Results The total effective rate of treatment in the combined group was higher than that in the control group(P<0.05).Compared with before treatment,the TCM symptom score,left and right resistance index,pulsatility index,serum luteini-zing hormone,follicle stimulating hormone and estradiol levels in the two groups were decreased after treatment,and the maximum blood flow velocity of uterine artery increased(P<0.05);and the change in the combined group was more obvi-ous than that in the control group(P<0.05).Conclusion Goserelin combined with Fukeqianjin capsule is safe and effective in the treatment of postoperative patients with endometriosis,and can improve their hemodynamics and estrogen levels.
作者 黄昌萍 李蓓 杨小蕾 HUANG Changping;LI Bei;YANG Xiaolei(Department of Obstetrics and Gynecology,Lianyungang Second People's Hospital,Lianyungang 222000,Jiangsu,China)
出处 《中南医学科学杂志》 CAS 2022年第5期744-746,761,共4页 Medical Science Journal of Central South China
关键词 戈舍瑞林 妇科千金胶囊 子宫内膜异位症 血流动力学 雌激素 goserelin Fukeqianjin capsule endometriosis hemodynamics estrogen
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