摘要
目的总结柴胡化学成分及药理作用的研究进展,为柴胡的质量控制及临床应用提供依据。方法查阅有关柴胡化学成分及药理作用的文献,并进行归纳、总结。结果柴胡中含有皂苷、挥发油、黄酮、多糖、炔类以及微量元素等成分,具有抗肿瘤、抗抑郁症、抗纤维化、降血脂、肝肺损伤保护等作用。结论柴胡化学成分和药理作用的研究已取得一定进展,但对于成分-药效-毒性的关系还需更深入研究。
Objective To summarize the research progress of chemical constituents and pharmacological action of Radix Bupleuri,and to provide basis for quality control and clinical application of Radix Bupleuri.Methods The literatures about chemical constituents and pharmacological action of Radix Bupleuri were reviewed and summarized.Results There are saponins,volatile oil,flavonoids,polysaccharides,alkynes and trace elements in Radix Bupleuri,which have the effects of anti-tumor,antidepression,anti-fibrosis,lowering blood lipid,liver and lung injury protection.Conclusion Some progress has been made in the study of chemical constituents and pharmacological action of Radix Bupleuri,but the relationship between composition,pharmacodynamics and toxicity needs further study.
作者
李艳凤
刘雅舒
李艳生
LI Yanfeng;LIU Yashu;LI Yansheng(School of Pharmacy,Heilongjiang University of Chinese Medicine,Key Laboratory of Basic and Application Research of Beiyao,Ministry of Education,Harbin 150040,China)
出处
《西北药学杂志》
CAS
2022年第5期186-192,共7页
Northwest Pharmaceutical Journal
基金
国家重点研发计划项目(编号:2018YFC1707000,黑龙江省“头雁”团队)。
关键词
柴胡
药理作用
化学成分
Radix Bupleuri
pharmacological action
saikosaponin
