摘要
Atherosclerosis is a chronic inflammatory vascular disease driven by traditional and nontraditional risk factors.Genome-wide association combined with clonal lineage tracing and clinical trials have demonstrated that innate and adaptive immune responses can promote or quell atherosclerosis.Several signaling pathways,that are associated with the inflammatory response,have been implicated within atherosclerosis such as NLRP3 inflammasome,toll-like receptors,proprotein convertase subtilisin/kexin type 9.
基金
This work was supported by the National Natural Science Foundation of China(91739301,91849102)
the Key Natural Science Foundation Projects of Hebei Province(H2019206028)
Natural Science Foundation of Hebei Province(H2021206006)
Natural Science Youth Fund of Hebei Province Education Department(QN2020167).
