摘要
功能性低聚糖是一类优质的益生元,具有促进肠道健康、降低血脂、增强免疫力等多种生理活性。但在制备过程中易产生非功能性糖分、色素以及无机盐等杂质。树脂具有吸附速度快、易再生、利用周期长等优点,被广泛应用于生物活性物质的富集纯化中。近年来,树脂在低聚糖分离纯化中的应用研究逐年增加,已逐渐成为国内外关注的新热点。本文重点对树脂在低聚糖分离、脱色、脱盐过程中的应用进行综述,并简述了树脂在低聚糖工业化生产中的应用,以期为低聚糖的纯化及后续应用提供基础。
Functional oligosaccharides are a kind of high quality prebiotics with various physiological activities such as promoting intestinal health,lowering blood lipids and enhancing immunity.However,non-functional sugars,pigments and inorganic salts are easily produced during the preparation process.Resin has the advantages of fast adsorption speed,easy regeneration and long utilization cycle,and is widely used in the enrichment and purification of bioactive substances.In recent years,the application of resin in the separation and purification of oligosaccharides has been increasing year by year,and has gradually become a new focus at home and abroad.In this paper,the application of different resins in the separation,decolorization and desalting of oligosaccharides was reviewed,and the application of resins in the industrial production of oligosaccharides was briefly introduced,in order to provide a basis for the purification and subsequent development of oligosaccharides.
作者
乔威杰
孙延平
王雨
匡海学
QIAO Wei-jie;SUN Yan-ping;WANG Yu;KUANG Hai-xue(Heilongjiang Key Laboratory of Traditional Chinese Medicine and Natural Medicine Pharmacodynamic Material Bases,Key Laboratory of Basic and Application Research of Beiyao(Heilongjiang University of Chinese Medicine),Ministry of Education,Heilongjiang University of Chinese Medicine,Harbin 150040,China)
出处
《化学工程师》
CAS
2022年第7期59-62,共4页
Chemical Engineer
基金
国家自然科学基金项目(81603282)
国家中医药管理局中医药传承与创新“百千万”人才工程-岐黄工程首席科学家支持项目(国中医药人教函[2021]7号)
国家中医药管理局中医药传承与创新“百千万”人才工程(岐黄工程)岐黄学者支持项目(国中医药人教函[2018]284号)
黑龙江省“头雁”团队支持项目(黑龙江省头雁行动领导小组文件[2019]5号)
黑龙江省博士后科研启动金资助项目(2021年)
黑龙江中医药大学“优秀青年教师支持计划”(2018RCQ05)
2022年全国名老中医药专家传承工作宝建设项目(国中医药人教函(2022)75号)
第七批全国老中医药专家学术经验继承人工作项目(国中医药人教函(2022)76号)
黑龙江省博后科研启动资金项目(No.LBH-Q21045)。
关键词
树脂
低聚糖
分离
脱色
脱盐
resin
oligosaccharides
separation
decolorization
desalination
