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中老年肺部感染住院患者医院感染的影响因素调查 被引量:2

Investigation on Influencing Factors of Nosocomial Infection in Middle-aged and Elderly Patients With Pulmonary Infection
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摘要 目的探讨中老年肺部感染住院患者医院感染的影响因素。方法选取2018年1月—2021年1月收治的中老年肺部感染住院患者600例进行回顾性分析,根据是否发生院内感染分为观察组(发生感染)与对照组(未发生感染)。统计两组患者年龄、性别、住院天数等一般资料以及基础疾病、侵入性操作等临床资料的差异,并对单因素分析结果有差异的观察指标进行Logistic回归分析。结果600例患者中共有62例发生院内感染,纳入观察组,余下538例纳入对照组。观察组与对照组患者在住院时间、吞咽困难、接受侵入性操作、应用呼吸机、合并慢性疾病、吸烟史方面差异有统计学意义(P<0.05)。Logistic回归方程显示住院时间>14 d、接受侵入性操作、应用呼吸机、合并慢性疾病、吸烟史是中老年肺部感染患者发生院内感染的独立危险因素(P<0.05)。结论临床上应根据中老年肺部感染患者的特点进行针对性干预,结合这类患者院内感染发生的危险因素进行防控。对于确诊发生的院内感染,在经验用药的基础上,要尽早分离培养致病菌,进行药敏试验,根据个人化差异使用耐药率低的抗菌药物进行干预。 Objective To investigate the influencing factors of nosocomial infection in elderly patients with pulmonary infection.Methods A retrospective analysis was conducted on 600 middleaged and elderly hospitalized patients with pulmonary infection from January 2018 to January 2021,and they were divided into observation group(with infection)and control group(without infection)according to whether nosocomial infection occurred.The differences of general data such as age,gender,length of stay and clinical data such as basic diseases and invasive procedures between the two groups were statistically analyzed,and Logistic regression analysis was conducted for the observation indicators with differences in univariate analysis results.Results Of the 600 patients,62 cases developed nosocomial infection and were included in the observation group,while the remaining 538 cases were included in the control group.There were significant differences between the observation group and the control group in terms of length of stay,dysphagia,invasive operation,ventilator application,chronic diseases and smoking history(P<0.05).Logistic regression equation showed that length of stay>14 d,invasive operation,ventilator application,chronic disease and smoking history were independent risk factors for nosocomial infection in middle-aged and elderly patients with pulmonary infection(P<0.05).Conclusion In clinical practice,targeted intervention should be carried out according to the characteristics of middle-aged and elderly patients with pulmonary infection,combined with the risk factors of nosocomial infection in these patients for prevention and control.For confirmed nosocomial infection,pathogens should be isolated and cultured as soon as possible,drug sensitivity test should be carried out,and antibiotics with low drug resistance rate should be used for intervention according to individual differences.
作者 曾宇 ZENG Yu(Infection Management Department,Meizhou Hospital of Traditional Chinese Medicine,Meizhou Guangdong 514021,China)
出处 《中国卫生标准管理》 2022年第12期152-155,共4页 China Health Standard Management
关键词 肺部感染 中老年患者 院内感染 回归分析 危险因素 并发症 lung infection middle-aged and elderly patients nosocomial infection regression analysis risk factors complications
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