摘要
糖尿病视网膜病变(DR)是糖尿病严重的慢性微血管并发症之一,是成人不可逆盲的主要原因之一,其发病机制复杂,至今尚未完全阐明。研究发现DR患者血清维生素D浓度与DR的发病及严重程度存在一定关系。本文从炎症、血管、神经、胰岛素抵抗等方面探讨维生素D在DR发生和发展中可能产生的作用及其机制,明确DR与血清维生素D浓度之间的关系。
Diabetic retinopathy(DR)is one of the most severe chronic complications of diabetes,which is the leading cause of blindness in working age population.The pathogenesis of DR is very complex and has not been elucidated completely.The development and severity of DR were shown to be linked to blood vitamin D concentrations.The goal of this review was to explain the link between diabetic retinopathy and vitamin D levels,as well as to explore the function of vitamin D in the development of DR and the mechanisms involved in inflammation,vascular disease,neurological disease,and insulin resistance.
作者
王一焮(综述)
姚勇(审校)
Wang Yixin;Yao Yong(Department of Ophthalmology,Wuxi People's Hospital Affiliated to Nanjing Medical University,Wuxi 214023,China)
出处
《中华实验眼科杂志》
CAS
CSCD
北大核心
2022年第7期690-694,共5页
Chinese Journal Of Experimental Ophthalmology
基金
国家自然科学基金项目(81770941)。
