摘要
目的:观察中药熏洗联合穴位贴敷治疗类风湿性关节炎的临床疗效。方法:选取2018年8月至2021年8月安阳市第二人民医院诊治的类风湿性关节炎患者80例,按照随机数字表法分为观察组和对照组,每组40例。对照组给予常规西药治疗,观察组在对照组治疗的基础上给予中药熏洗联合穴位贴敷治疗。观察两组患者临床疗效及治疗前后中医证候评分、关节功能情况(肿胀指数评分、压痛指数评分、晨僵时间)、关节活动度及实验室指标[血沉(erythrocyte sedimentation rate,ESR)、C反应蛋白(C reactive protein,CRP)、白细胞介素-37(interleukin-37,IL-37)、可溶性PD-1(soluble PD-1,sPD-1)]检测结果的变化情况。结果:观察组有效率为95.00%,对照组有效率为80.00%,观察组有效率高于对照组,差异有统计学意义(P<0.05);观察组治疗后中医证候评分低于对照组,差异有统计学意义(P<0.05);两组治疗后肿胀指数评分、压痛指数评分、DAS28评分均低于治疗前,晨僵时间短于治疗前,且观察组治疗后肿胀指数评分、压痛指数评分、DAS28评分均低于对照组,晨僵时间短于对照组,差异有统计学意义(P<0.05);两组治疗后ESR、CRP、IL-37、sPD-1水平均低于治疗前,观察组治疗后ESR、CRP、IL-37、sPD-1水平均低于对照组,差异有统计学意义(P<0.05)。结论:中药熏洗联合穴位贴敷治疗类风湿性关节炎,能够有效改善患者临床症状和关节活动度。
Objective:To observe the clinical efficacy of fumigation and washing with Chinese medicinals combined with acupoint application on rheumatoid arthritis.Methods:A total of 80 patients with rheumatoid arthritis diagnosed and treated in Anyang Sec-ond People′s Hospital from August 2018 to August 2021 were randomly divided into the observation group and the control group,with 40 cases in each group.The control group was treated with conventional Western medicine,while the observation group was treated with fumigation and washing with Chinese medicinals combined with acupoint application on the basis of the treatment of the control group.The clinical efficacy and the changes of TCM syndrome score,joint function(such as swelling index score,ten-derness index score,morning stiffness time),joint range of motion and laboratory indexes[including erythrocyte sedimentation rate(ESR),C reactive protein(CRP),interleukin-37(IL-37),soluble PD-1(sPD-1)]detection results before and after treatment were observed.Results:The effective rate was 95.00%in the observation group and 80.00%in the control group.The effective rate in the observation group was significantly higher than that in the control group,and the difference was statistically significant(P<0.05).The score of TCM syndrome in the observation group was lower than that in the control group after treatment,and the difference was statistically significant(P<0.05).The swelling index score,tenderness index score and DAS28 score of the two groups after treatment were lower than those before treatment,and the morning stiffness time was shorter than that before treatment.The swelling index score,tenderness index score and DAS28 score of the observation group after treatment were lower than those of the control group,and the morning stiffness time was shorter than that of the control group,and all the differences were statistically significant(P<0.05).After treatment,the levels of ESR,CRP,IL-37 and sPD-1 in the two groups were lower than those before treatment.And the above indexes in the observation group were lower than those in the control group.All the differences were sta-tistically significant(P<0.05).Conclusion:Fumigation and washing with Chinese medicinals combined with acupoint application can effectively improve the clinical symptoms and joint range of motion of patients with rheumatoid arthritis.
作者
李玲
LI Ling(Anyang Second People′s Hospital,Anyang,Henan,China,455100)
出处
《河南中医》
2022年第9期1425-1428,共4页
Henan Traditional Chinese Medicine
基金
河南省科技攻关计划项目(2018020726)。
关键词
类风湿性关节炎
中药熏洗
穴位贴敷
关节活动度
rheumatoid arthritis
fumigation and washing with Chinese medicinals
acupoint application
joint range of motion
