摘要
目的:探讨强脉冲光(Intense pulsed light,IPL)联合超脉冲点阵CO_(2)激光治疗皮肤光老化的疗效,并分析其不良反应的发生情况。方法:选取2018年3月-2020年10月在笔者医院皮肤科就诊的皮肤光老化就医者118例。采用随机数字法分为对照组和观察组,各59例。对照组应用IPL进行修复,观察组在对照组基础上联合超脉冲点阵CO_(2)激光进行修复。比较两组临床疗效、VISIA评分及安全性。结果:观察组总有效率(96.61%)高于对照组总有效率(81.36%),差异有统计学意义(P<0.05)。治疗后,两组色斑、皱纹、纹理、毛孔数值评分均低于治疗前,且观察组均低于对照组,差异均有统计学意义(P<0.05)。观察组不良反应总发生率(5.08%)低于对照组不良反应总发生率(16.95%),差异有统计学意义(P<0.05)。结论:IPL联合超脉冲点阵CO_(2)激光在治疗皮肤光老化中效果显著,可提高皮肤质地,改善光老化症状,减少不良反应,安全性高,值得推广临床应用。
Objective To investigate the effi cacy and safety of intense pulsed light(IPL)combined with ultra-pulse fractional CO_(2) laser in the treatment of skin photoaging.Methods Total of 118 patients with skin photoaging who were treated in the dermatology department of author hospital from March 2018 to October 2020 were selected.According to the random number method,the patients with skin photoaging were divide into the control group(n=59)and the observation group(n=59).The patients with skin photoaging in the control group was treated with IPL,and the patients with skin photoaging in the observation group was treated with IPL combined with ultra-pulse fractional CO_(2) laser.The clinical effi cacy,VISIA scores and adverse reactions of the two groups were compared.Results The total eff ective rate of the observation group(96.61%)was higher than that of the control group(81.36%),and the diff erence was statistically signifi cant(P<0.05).After treatment,the VISIA scores of stains,wrinkles,texture,and pores in the two groups were lower than before treatment,and the scores of the observation group were lower than that of the control group,and the diff erence were all statistically signifi cant(P<0.05).The total incidence of adverse reactions in the observation group(5.08%)was lower than that in the control group(16.95%),and the difference was statistically significant(P<0.05).Conclusion IPL combined with ultra-pulse fractional CO_(2) laser has a signifi cant eff ect in the treatment of skin photoaging,which can improve skin texture,improve photoaging symptoms,reduce the occurrence of adverse reactions,and has good safety and is worth promoting clinical application.
作者
陈诚
肖洁银
余梦
CHEN Cheng;XIAO Jieyin;YU Meng(Department of Dermatology,Wuhan No.1 Hospital,Wuhan 430000,Hubei,China)
出处
《中国美容医学》
CAS
2022年第7期1-4,共4页
Chinese Journal of Aesthetic Medicine
